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Veronica A Alvarez

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Articles 58
Citations 3038
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Recent Articles
1.
Shin J, Goldbach H, Burke D, Authement M, Swanson E, Bocarsly M, et al.
J Neurosci . 2025 Jan; 45(11). PMID: 39837662
Dopamine critically regulates neuronal excitability and promotes synaptic plasticity in the striatum, thereby shaping network connectivity and influencing behavior. These functions establish dopamine as a key neuromodulator, whose release properties...
2.
Bocarsly M, Shaw M, Ventriglia E, Anderson L, Goldbach H, Teresi C, et al.
Nat Commun . 2024 Oct; 15(1):9093. PMID: 39438478
Alcohol use disorder (AUD) is frequently comorbid with anxiety disorders, yet whether alcohol abuse precedes or follows the expression of anxiety remains unclear. Rodents offer control over the first drink,...
3.
Furlanis E, Dai M, Garcia B, Vergara J, Pereira A, Pelkey K, et al.
bioRxiv . 2024 Aug; PMID: 39091835
In recent years, we and others have identified a number of enhancers that, when incorporated into rAAV vectors, can restrict the transgene expression to particular neuronal populations. Yet, viral tools...
4.
Xi Z, Bocarsly M, Galaj E, Hempel B, Teresi C, Shaw M, et al.
Biol Psychiatry . 2024 Jun; 96(9):752-765. PMID: 38838841
Background: Past research has illuminated pivotal roles of dopamine D receptors (DR) in the rewarding effects of cocaine and opioids. However, the cellular and neural circuit mechanisms that underlie these...
5.
Guerri L, Dobbs L, da Silva E Silva D, Meyers A, Ge A, Lecaj L, et al.
Biol Psychiatry Glob Open Sci . 2023 Oct; 3(4):1104-1115. PMID: 37881572
Background: A salient effect of addictive drugs is to hijack the dopamine reward system, an evolutionarily conserved driver of goal-directed behavior and learning. Reduced dopamine type 2 receptor availability in...
6.
da Silva D, Matsui A, Murray E, Mamais A, Authement M, Shin J, et al.
Neuropsychopharmacology . 2023 Sep; 49(5):824-836. PMID: 37684522
The transition from hedonic alcohol drinking to problematic drinking is a hallmark of alcohol use disorder that occurs only in a subset of drinkers. This transition requires long-lasting changes in...
7.
Levenstein D, Alvarez V, Amarasingham A, Azab H, Chen Z, Gerkin R, et al.
J Neurosci . 2023 Feb; 43(7):1074-1088. PMID: 36796842
In recent years, the field of neuroscience has gone through rapid experimental advances and a significant increase in the use of quantitative and computational methods. This growth has created a...
8.
Dai K, Choi I, Levitt R, Blegen M, Kaplan A, Matsui A, et al.
Cell Rep . 2022 Sep; 40(13):111440. PMID: 36170833
Low dopamine D2 receptor (D2R) availability in the striatum can predispose for cocaine abuse; though how low striatal D2Rs facilitate cocaine reward is unclear. Overexpression of D2Rs in striatal neurons...
9.
Razidlo J, Fausner S, Ingebretson A, Wang L, Petersen C, Mirza S, et al.
J Neurosci . 2022 Jul; 42(36):6917-6930. PMID: 35896424
There are five cloned muscarinic acetylcholine receptors (M1-M5). Of these, the muscarinic type 5 receptor (M5) is the only one localized to dopamine neurons in the ventral tegmental area and...
10.
Burke D, Alvarez V
Cell Rep . 2022 May; 39(6):110795. PMID: 35545050
Dopamine modulation of nucleus accumbens (NAc) circuitry is central to theories of reward seeking and reinforcement learning. Despite decades of effort, the acute dopamine actions on the NAc microcircuitry remain...