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Verena Waller

Explore the profile of Verena Waller including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 120
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Recent Articles
1.
Waller V, Tschanz F, Winkler R, Pruschy M
Front Oncol . 2023 Mar; 13:1117326. PMID: 36998455
Purpose: Ionizing radiation (IR) enhances the migratory capacity of cancer cells. Here we investigate in non-small-cell-lung-cancer (NSCLC) cells a novel link between IR-enhanced ADAM17 activity and the non-canonical pathway of...
2.
Tschanz F, Bender S, Telarovic I, Waller V, Speck R, Pruschy M
Cancer Res Commun . 2023 Mar; 1(3):164-177. PMID: 36860547
Significance: The tumor response to radiotherapy is influenced by several factors of the tumor microenvironment. We demonstrate that inhibition of the sheddase ADAM17 by the novel antibody MEDI3622 reduces IR-induced...
3.
Roas M, Vick B, Kasper M, Able M, Polzer H, Gerlach M, et al.
Blood . 2022 Aug; 141(9):1023-1035. PMID: 35981498
Fms-like tyrosine kinase 3 (FLT3) is often overexpressed or constitutively activated by internal tandem duplication (ITD) and tyrosine kinase domain (TKD) mutations in acute myeloid leukemia (AML). Despite the use...
4.
Deycmar S, Mara E, Kerschbaum-Gruber S, Waller V, Georg D, Pruschy M
Radiat Oncol . 2022 Apr; 17(1):72. PMID: 35410422
Objective: Hypersensitivity towards proton versus photon irradiation was demonstrated in homologous recombination repair (HRR)-deficient cell lines. Hence, combined treatment concepts targeting HRR provide a rational for potential pharmaceutical exploitation. The...
5.
Plomecka M, Gobbi S, Neckels R, Radzinski P, Skorko B, Lazzeri S, et al.
JMIR Ment Health . 2021 Jul; 8(8):e28736. PMID: 34254939
Background: Accumulating evidence suggests that the COVID-19 pandemic has negatively impacted the mental health of individuals. However, the susceptibility of individuals to be impacted by the pandemic is variable, suggesting...
6.
La Greca Saint-Esteven A, Vuong D, Tschanz F, van Timmeren J, Dal Bello R, Waller V, et al.
Cancers (Basel) . 2021 Jul; 13(12). PMID: 34208595
Radiomics supposes an alternative non-invasive tumor characterization tool, which has experienced increased interest with the advent of more powerful computers and more sophisticated machine learning algorithms. Nonetheless, the incorporation of...
7.
Waller V, Pruschy M
Front Oncol . 2021 May; 11:676583. PMID: 34055644
Besides cytotoxic DNA damage irradiation of tumor cells triggers multiple intra- and intercellular signaling processes, that are part of a multilayered, treatment-induced stress response at the unicellular and tumor pathophysiological...
8.
Gobbi S, Plomecka M, Ashraf Z, Radzinski P, Neckels R, Lazzeri S, et al.
Front Psychiatry . 2021 Jan; 11:581426. PMID: 33391049
To ascertain factors associated with worsening of psychiatric conditions during the coronavirus disease 2019 (COVID-19) pandemic. This study anonymously examined 2,734 psychiatric patients worldwide for worsening of their preexisting psychiatric...
9.
Deycmar S, Faccin E, Kazimova T, Knobel P, Telarovic I, Tschanz F, et al.
Br J Radiol . 2019 Nov; 93(1107):20190494. PMID: 31687835
Clinical parameters and empirical evidence are the primary determinants for current treatment planning in radiation oncology. Personalized medicine in radiation oncology is only at the very beginning to take the...
10.
Schumacher D, Lemke O, Helma J, Gerszonowicz L, Waller V, Stoschek T, et al.
Chem Sci . 2017 May; 8(5):3471-3478. PMID: 28507719
The broad substrate tolerance of tubulin tyrosine ligase is the basic rationale behind its wide applicability for chemoenzymatic protein functionalization. In this context, we report that the wild-type enzyme enables...