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Vera M Poort

Explore the profile of Vera M Poort including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 35
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Recent Articles
1.
Derks L, van Leeuwen A, Steemers A, Trabut L, van Roosmalen M, Poort V, et al.
STAR Protoc . 2024 Dec; 6(1):103499. PMID: 39709610
The study of somatic mutations in single cells provides insights into aging and carcinogenesis, which is complicated by the dependency on whole-genome amplification (WGA). Here, we describe a detailed workflow...
2.
Poort V, Hagelaar R, van Roosmalen M, Trabut L, Buijs-Gladdines J, van Wijk B, et al.
Cancer Res . 2024 Jun; 84(16):2720-2733. PMID: 38885294
Leukemia is characterized by oncogenic lesions that result in a block of differentiation, whereas phenotypic plasticity is retained. A better understanding of how these two phenomena arise during leukemogenesis in...
3.
Cordo V, Meijer M, Hagelaar R, de Goeij-de Haas R, Poort V, Henneman A, et al.
Nat Commun . 2022 Feb; 13(1):1048. PMID: 35217681
Protein kinase inhibitors are amongst the most successful cancer treatments, but targetable kinases activated by genomic abnormalities are rare in T cell acute lymphoblastic leukemia. Nevertheless, kinases can be activated...
4.
Kroeze E, Loeffen J, Poort V, Meijerink J
Blood Adv . 2020 Jul; 4(14):3466-3473. PMID: 32722786
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent malignancies that arise from the transformation of immature precursor T cells. Similarities in T-LBL and T-ALL have raised the question whether...