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Vera Guber

Explore the profile of Vera Guber including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 428
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Recent Articles
1.
Hata M, Hata M, Andriessen E, Juneau R, Pilon F, Crespo-Garcia S, et al.
J Clin Invest . 2023 Feb; 133(4). PMID: 36787231
Pathological neovascularization in age-related macular degeneration (nvAMD) drives the principal cause of blindness in the elderly. While there is a robust genetic association between genes of innate immunity and AMD,...
2.
Hata M, Andriessen E, Hata M, Diaz-Marin R, Fournier F, Crespo-Garcia S, et al.
Science . 2023 Jan; 379(6627):45-62. PMID: 36603072
Age-related macular degeneration is a prevalent neuroinflammatory condition and a major cause of blindness driven by genetic and environmental factors such as obesity. In diseases of aging, modifiable factors can...
3.
Crespo-Garcia S, Tsuruda P, Dejda A, Ryan R, Fournier F, Chaney S, et al.
Cell Metab . 2021 Feb; 33(4):818-832.e7. PMID: 33548171
Attenuating pathological angiogenesis in diseases characterized by neovascularization such as diabetic retinopathy has transformed standards of care. Yet little is known about the molecular signatures discriminating physiological blood vessels from...
4.
Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, et al.
Science . 2020 Aug; 369(6506). PMID: 32820093
In developed countries, the leading causes of blindness such as diabetic retinopathy are characterized by disorganized vasculature that can become fibrotic. Although many such pathological vessels often naturally regress and...
5.
Miloudi K, Oubaha M, Menard C, Dejda A, Guber V, Cagnone G, et al.
Proc Natl Acad Sci U S A . 2019 Feb; 116(10):4538-4547. PMID: 30787185
Diabetic macular edema is a major complication of diabetes resulting in loss of central vision. Although heightened vessel leakiness has been linked to glial and neuronal-derived factors, relatively little is...
6.
Oubaha M, Miloudi K, Dejda A, Guber V, Mawambo G, Germain M, et al.
Sci Transl Med . 2016 Nov; 8(362):362ra144. PMID: 27797960
Pathological angiogenesis is the hallmark of diseases such as cancer and retinopathies. Although tissue hypoxia and inflammation are recognized as central drivers of vessel growth, relatively little is known about...