Venkat N Reddy
Overview
Explore the profile of Venkat N Reddy including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
411
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Recent Articles
1.
Yang D, Elner S, Lin L, Reddy V, Petty H, Elner V
Invest Ophthalmol Vis Sci
. 2009 May;
50(10):4998-5005.
PMID: 19458341
Purpose: Oxidative stress of the retinal pigment epithelium by reactive oxygen species and monocytic infiltration have been implicated in age-related macular degeneration. The purpose of this study was to determine...
2.
Wang H, Gao J, Sun X, Martinez-Wittinghan F, Li L, Varadaraj K, et al.
J Membr Biol
. 2008 Dec;
227(1):25-37.
PMID: 19067024
Glutathione peroxidase-1 (GPX-1) is an enzyme that protects the lens against H2O2-mediated oxidative damage. The purpose of the present study was to determine the effects of GPX-1 knockout (KO) on...
3.
Shibuya M, Okamoto H, Nozawa T, Utsumi J, Reddy V, Echizen H, et al.
Invest Ophthalmol Vis Sci
. 2007 Jan;
48(2):516-21.
PMID: 17251444
Purpose: The authors previously reported a growth-promoting factor, REF-1/TFPI-2, that is specific to retinal pigment epithelial (RPE) cells. The purpose of this study was to determine the genes and proteins...
4.
Bucolo C, Drago F, Lin L, Reddy V
Neuroreport
. 2006 Feb;
17(3):287-91.
PMID: 16462599
This study was undertaken to investigate the role of sigma receptors during the oxidative damage on human retinal pigment epithelial cells, and to assess whether sigma receptor ligands enhance survival...
5.
Kasahara E, Lin L, Ho Y, Reddy V
Invest Ophthalmol Vis Sci
. 2005 Aug;
46(9):3426-34.
PMID: 16123448
Purpose: Oxidative stress from reactive oxygen species (ROS) has been implicated in many diseases, including age-related macular degeneration (AMD), in which the retinal pigment epithelium (RPE) is considered a primary...
6.
Bucolo C, Drago F, Lin L, Reddy V
Neuroreport
. 2005 Jul;
16(11):1203-7.
PMID: 16012349
This study was undertaken to assess whether neuroactive steroids, 17beta-estradiol and dehydroepiandrosterone-sulfate, enhance survival and protect DNA of human retinal pigment epithelial cells challenged by oxidative stress, and to investigate...
7.
Oharazawa H, Ibaraki N, Ohara K, Reddy V
Ophthalmic Res
. 2005 Jul;
37(4):191-6.
PMID: 15990462
Posterior capsule opacification (PCO) after cataract surgery is caused by growth of residual human lens epithelial (HLE) cells on the posterior capsule. We have shown that extracellular matrix (ECM) is...
8.
Marques C, Pereira P, Taylor A, Liang J, Reddy V, Szweda L, et al.
FASEB J
. 2004 Jul;
18(12):1424-6.
PMID: 15247152
4-hydroxynonenal (HNE), a highly reactive lipid peroxidation product, may adversely modify proteins. Accumulation of HNE-modified proteins may be responsible for pathological lesions associated with oxidative stress. The objective of this...
9.
Kantorow M, Hawse J, Cowell T, Benhamed S, Pizarro G, Reddy V, et al.
Proc Natl Acad Sci U S A
. 2004 Jun;
101(26):9654-9.
PMID: 15199188
Age-related cataract, an opacity of the eye lens, is the leading cause of visual impairment in the elderly, the etiology of which is related to oxidative stress damage. Oxidation of...
10.
Oravecz-Wilson K, Kiel M, Li L, Rao D, Saint-Dic D, Kumar P, et al.
Hum Mol Genet
. 2004 Mar;
13(8):851-67.
PMID: 14998932
Huntingtin Interacting Protein 1 (HIP1) binds clathrin and AP2, is overexpressed in multiple human tumors, and transforms fibroblasts. The function of HIP1 is unknown although it is thought to play...