Velen L Nelson-Degrave
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Explore the profile of Velen L Nelson-Degrave including associated specialties, affiliations and a list of published articles.
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9
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292
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Recent Articles
1.
Wickenheisser J, Biegler J, Nelson-Degrave V, Legro R, Strauss 3rd J, McAllister J
PLoS One
. 2012 Nov;
7(11):e48963.
PMID: 23155436
Hyperandrogenism is characteristic of women with polycystic ovary syndrome (PCOS). Ovarian theca cells isolated from PCOS follicles and maintained in long-term culture produce elevated levels of progestins and androgens compared...
2.
Wickenheisser J, Nelson-Degrave V, McAllister J
Trends Endocrinol Metab
. 2006 Feb;
17(2):65-71.
PMID: 16460956
Elucidating the regulation of androgen biosynthesis in ovarian theca cells is not only important for determining the mechanisms of regulation of estrogen biosynthesis throughout the menstrual cycle, but is also...
3.
Wickenheisser J, Nelson-Degrave V, Hendricks K, Legro R, Strauss 3rd J, McAllister J
J Clin Endocrinol Metab
. 2005 May;
90(8):4858-65.
PMID: 15914525
Context: Polycystic ovary syndrome (PCOS) is characterized by ovarian androgen excess and infertility. Recent experiments have suggested that several genes involved in retinoic acid synthesis may be differentially expressed in...
4.
Wood J, Nelson-Degrave V, Jansen E, McAllister J, Mosselman S, Strauss 3rd J
Physiol Genomics
. 2004 Dec;
20(3):233-43.
PMID: 15598877
Valproic acid (VPA) is an anti-epileptic drug that has been associated with polycystic ovary syndrome (PCOS)-like symptoms, including increased ovarian androgen production. The hyperandrogenemia likely reflects the stimulatory action of...
5.
Wickenheisser J, Nelson-Degrave V, McAllister J
J Clin Endocrinol Metab
. 2004 Dec;
90(3):1720-7.
PMID: 15598676
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by ovarian hyperandrogenism. Theca interna cells isolated from the ovaries of women with PCOS are characterized by increased expression...
6.
Nelson-Degrave V, Wickenheisser J, Hendricks K, Asano T, Fujishiro M, Legro R, et al.
Mol Endocrinol
. 2004 Oct;
19(2):379-90.
PMID: 15514033
We have investigated the involvement of the MAPK signaling pathway in increased androgen biosynthesis and CYP17 gene expression in women with polycystic ovary syndrome (PCOS). A comparison of MAPK kinase...
7.
Wood J, Ho C, Nelson-Degrave V, McAllister J, Strauss 3rd J
J Reprod Immunol
. 2004 Jul;
63(1):51-60.
PMID: 15284005
Polycystic ovary syndrome (PCOS) is characterized by increased ovarian androgen secretion, anovulatory infertility due to arrested folliculogenesis, and is frequently found in association with insulin resistance and obesity. Characterization of...
8.
Wickenheisser J, Nelson-Degrave V, Quinn P, McAllister J
Mol Endocrinol
. 2003 Dec;
18(3):588-605.
PMID: 14684846
Cytochrome P450 17alpha-hydroxylase (CYP17) gene expression and androgen biosynthesis are persistently elevated in theca cells isolated from ovaries of women with polycystic ovary syndrome (PCOS). We previously reported that -235...
9.
Nelson-Degrave V, Wickenheisser J, Cockrell J, Wood J, Legro R, Strauss 3rd J, et al.
Endocrinology
. 2003 Oct;
145(2):799-808.
PMID: 14576182
In patients with epilepsy, treatment with valproate (VPA) has been reported to be associated with polycystic ovary syndrome-like symptoms including weight gain, hyperandrogenemia, and hyperinsulinemia. We examined the effect of...