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Vasthi Lopez

Explore the profile of Vasthi Lopez including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 181
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Recent Articles
1.
Moraga F, Reyes R, Ebensperger G, Lopez V, Llanos A
Front Physiol . 2021 Aug; 12:697211. PMID: 34421636
The authors previously demonstrated that newborn llama (NBLL) express high levels of α adrenergic receptors, which provide a potent vasoconstriction response when compared with newborn sheep (NBSH) gestated at sea...
2.
Lopez V, Uribe E, Moraga F
Hypertens Res . 2020 Nov; 44(3):263-275. PMID: 33149269
In recent years, the increase in blood pressure at high altitudes has become an interesting topic among high-altitude researchers. In our animal studies using Wistar rats, we observed the existence...
3.
Reyes M, Martinez-Oyanedel J, Navarrete C, Mardones E, Martinez I, Salas M, et al.
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32531922
Agmatine is a neurotransmitter with anticonvulsant, anti-neurotoxic and antidepressant-like effects, in addition it has hypoglycemic actions. Agmatine is converted to putrescine and urea by agmatinase (AGM) and by an agmatinase-like...
4.
Lobos M, Figueroa M, Martinez-Oyanedel J, Lopez V, de Los Angeles Garcia-Robles M, Tarifeno-Saldivia E, et al.
J Struct Biol . 2020 May; 211(2):107533. PMID: 32450233
Arginase (EC 3.5.3.1) catalyzes the hydrolysis of L-arginine to L-ornithine and urea, and requires a bivalent cation, especially Mn for its catalytic activity. It is a component of the urea...
5.
Uribe E, Reyes M, Martinez I, Mella K, Salas M, Tarifeno-Saldivia E, et al.
J Inorg Biochem . 2019 Nov; 202:110812. PMID: 31731096
Ureohydrolases form a conserved family of enzymes with a strict requirement for divalent metal ions for catalytic activity. They catalyze the hydrolysis of the guanidino group and produce urea. In...
6.
Lopez V, Moraga F, Llanos A, Ebensperger G, Taborda M, Uribe E
Front Physiol . 2018 Jun; 9:606. PMID: 29896110
Method: Lowland and highland newborn sheep and llama were investigated near sea level and at high altitude. Blood determinations of arterial blood gases, ADMA and homocysteíne are made and the...
7.
Moraga F, Miranda G, Lopez V, Vallejos C, Silva D
High Alt Med Biol . 2018 Mar; 19(2):149-155. PMID: 29565678
Background: Previous studies performed in rats exposed to chronic intermittent hypobaric hypoxia (CIHH), at a simulated altitude of 4600 m, showed reduced nitric oxide (NO) production, increased arginase activity, and...
8.
Benitez J, Garcia D, Romero N, Gonzalez A, Martinez-Oyanedel J, Figueroa M, et al.
Metabolism . 2017 Nov; 81:35-44. PMID: 29162499
Agmatine (1-amino-4-guanidinobutane), a precursor for polyamine biosynthesis, has been identified as an important neuromodulator with anticonvulsant, antineurotoxic and antidepressant actions in the brain. In this context it has emerged as...
9.
Romero N, Benitez J, Garcia D, Gonzalez A, Bennun L, Garcia-Robles M, et al.
J Inorg Biochem . 2016 Nov; 166:122-125. PMID: 27846445
Agmatine (1-amino-4-guanidinobutane) plays an important role in a range of metabolic functions, in particular in the brain. Agmatinases (AGMs) are enzymes capable of converting agmatine to the polyamine putrescine and...
10.
Garcia D, Ordenes P, Benitez J, Gonzalez A, Garcia-Robles M, Lopez V, et al.
Histochem Cell Biol . 2015 Dec; 145(3):305-13. PMID: 26678503
Agmatine, a precursor for polyamine biosynthesis, is also associated with neurotransmitter, anticonvulsant, antineurotoxic and antidepressant actions in the brain. This molecule results from the decarboxylation of L-arginine by arginine decarboxylase,...