Vasilisa Aksenova
Overview
Explore the profile of Vasilisa Aksenova including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
226
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Recent Articles
1.
PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities
Lama B, Park H, Saraf A, Hassebroek V, Keifenheim D, Saito-Fujita T, et al.
Life Sci Alliance
. 2025 Feb;
8(4).
PMID: 39919802
Either inhibiting or stabilizing SUMOylation in mitosis causes defects in chromosome segregation, suggesting that dynamic mitotic SUMOylation of proteins is critical to maintain integrity of the genome. Polo-like kinase 1-interacting...
2.
Xie Y, Clarke B, Xie D, Mei M, Bhat P, Hill P, et al.
Structure
. 2025 Jan;
33(3):566-582.e6.
PMID: 39862860
mRNAs are packaged with proteins into messenger ribonucleoprotein complexes (mRNPs) in the nucleus. mRNP assembly and export are of fundamental importance for all eukaryotic gene expression. Before export to the...
3.
Zhang K, Cagatay T, Xie D, Angelos A, Cornelius S, Aksenova V, et al.
J Biol Chem
. 2024 Oct;
300(11):107871.
PMID: 39384042
Influenza A viruses have eight genomic RNAs that are transcribed in the host cell nucleus. Two of the viral mRNAs undergo alternative splicing. The M1 mRNA encodes the matrix protein...
4.
Schooley A, Venev S, Aksenova V, Navarrete E, Dasso M, Dekker J
bioRxiv
. 2024 Sep;
PMID: 39345587
Identity-specific interphase chromosome conformation must be re-established each time a cell divides. To understand how interphase folding is inherited, we developed an experimental approach that physically segregates mediators of G1...
5.
Bhat P, Aksenova V, Gazzara M, Rex E, Aslam S, Haddad C, et al.
Nat Commun
. 2023 Apr;
14(1):2304.
PMID: 37085480
Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the...
6.
LaJoie D, Turkmen A, Mackay D, Jensen C, Aksenova V, Niwa M, et al.
Mol Biol Cell
. 2022 Aug;
33(13):ar117.
PMID: 36044344
Assembly of the nucleus following mitosis requires rapid and coordinate recruitment of diverse constituents to the inner nuclear membrane. We have identified an unexpected role for the nucleoporin Nup153 in...
7.
Duan L, Zaepfel B, Aksenova V, Dasso M, Rothstein J, Kalab P, et al.
Cell Rep
. 2022 Jul;
40(3):111106.
PMID: 35858577
Nuclear clearance of the RNA-binding protein TDP-43 is a hallmark of neurodegeneration and an important therapeutic target. Our current understanding of TDP-43 nucleocytoplasmic transport does not fully explain its predominantly...
8.
Gao S, Esparza M, Dehghan I, Aksenova V, Zhang K, Batten K, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(25):e2206046119.
PMID: 35704758
Nuclear speckles are non-membrane-bound organelles known as storage sites for messenger RNA (mRNA) processing and splicing factors. More recently, nuclear speckles have also been implicated in splicing and export of...
9.
Aksenova V, Arnaoutov A, Dasso M
Methods Mol Biol
. 2022 Apr;
2502:129-150.
PMID: 35412236
Over the last decade, the use of auxin-inducible degrons (AID) to control the stability of target proteins has revolutionized the field of cell biology. AID-mediated degradation helps to overcome multiple...
10.