Vanessa Dumeaux
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Explore the profile of Vanessa Dumeaux including associated specialties, affiliations and a list of published articles.
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53
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1305
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Recent Articles
1.
Pepin A, Jazwiec P, Dumeaux V, Sloboda D, Kimmins S
Elife
. 2024 Nov;
13.
PMID: 39612469
Paternal obesity has been implicated in adult-onset metabolic disease in offspring. However, the molecular mechanisms driving these paternal effects and the developmental processes involved remain poorly understood. One underexplored possibility...
2.
Lismer A, Shao X, Dumargne M, Lafleur C, Lambrot R, Chan D, et al.
Environ Health Perspect
. 2024 Jan;
132(1):17008.
PMID: 38294233
Background: The organochlorine dichlorodiphenyltrichloroethane (DDT) is banned worldwide owing to its negative health effects. It is exceptionally used as an insecticide for malaria control. Exposure occurs in regions where DDT...
3.
Rowland M, Jiang Y, Shafiq S, Ghahramani A, Pena-Ortiz M, Dumeaux V, et al.
Nat Commun
. 2023 Nov;
14(1):7090.
PMID: 37925436
Myelin, an extension of the oligodendrocyte plasma membrane, wraps around axons to facilitate nerve conduction. Myelination is compromised in ATR-X intellectual disability syndrome patients, but the causes are unknown. We...
4.
Dumeaux V, Massahi S, Bettauer V, Mottola A, Dukovny A, Khurdia S, et al.
Elife
. 2023 Oct;
12.
PMID: 37888959
an opportunistic human pathogen, poses a significant threat to human health and is associated with significant socio-economic burden. Current antifungal treatments fail, at least in part, because can initiate a...
5.
Jeyarajah M, Jaju Bhattad G, Kelly R, Baines K, Jaremek A, Yang F, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(49):e2203071119.
PMID: 36442132
Remodeling of the uterine vasculature by invasive extravillous trophoblasts (EVTs) is a critical aspect of human placentation. Insufficient EVT invasion can lead to severe obstetrical complications like preeclampsia, intrauterine growth...
6.
Bettauer V, Costa A, Omran R, Massahi S, Kirbizakis E, Simpson S, et al.
Microbiol Spectr
. 2022 Aug;
10(5):e0147222.
PMID: 35972285
We present deep learning-based approaches for exploring the complex array of morphologies exhibited by the opportunistic human pathogen Candida albicans. Our system, entitled Candescence, automatically detects C. albicans cells from...
7.
Pepin A, Lafleur C, Lambrot R, Dumeaux V, Kimmins S
Mol Metab
. 2022 Feb;
59:101463.
PMID: 35183795
Objective: Parental environmental exposures can strongly influence descendant risks for adult disease. How paternal obesity changes the sperm chromatin leading to the acquisition of metabolic disease in offspring remains controversial...
8.
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans
Omran R, Ramirez-Zavala B, Aji Tebung W, Yao S, Feng J, Law C, et al.
Genetics
. 2021 Dec;
220(1).
PMID: 34849863
Zinc cluster transcription factors (TFs) are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster TF regulating filament development. Hyperactivation of...
9.
Lambrot R, Chan D, Shao X, Aarabi M, Kwan T, Bourque G, et al.
Cell Rep
. 2021 Jul;
36(3):109418.
PMID: 34289352
The paternal environment has been linked to infertility and negative outcomes. Such effects may be transmitted via sperm through histone modifications. To date, in-depth profiling of the sperm chromatin in...
10.
Lismer A, Lambrot R, Lafleur C, Dumeaux V, Kimmins S
STAR Protoc
. 2021 Jun;
2(2):100602.
PMID: 34159325
In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descendants has been elusive. This protocol details how to track sperm chromatin...