Valerie Y H van Weperen
Overview
Explore the profile of Valerie Y H van Weperen including associated specialties, affiliations and a list of published articles.
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14
Citations
60
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Recent Articles
1.
Hoang J, van Weperen V, Kang K, Jani N, Swid M, Chan C, et al.
Circ Res
. 2024 Jun;
135(3):e57-e75.
PMID: 38939925
Background: Thoracic epidural anesthesia (TEA) has been shown to reduce the burden of ventricular tachycardia in small case series of patients with refractory ventricular tachyarrhythmias and cardiomyopathy. However, its electrophysiological...
2.
van Weperen V, Hoang J, Jani N, Khaky A, Herring N, Smith C, et al.
J Physiol
. 2024 Feb;
PMID: 38352977
Cardiac disease is marked by sympathoexcitation and elevated levels of noradrenaline (NA) and cotransmitter neuropeptide Y (NPY). Increased NPY levels are associated with a greater risk of ventricular arrhythmias and...
3.
Loen V, van Weperen V, Beekman H, Van Bavel J, Meijborg V, Van der Waal J, et al.
Front Physiol
. 2024 Jan;
14:1330230.
PMID: 38179141
An electrical storm of Torsade de Pointes arrhythmias (TdP) can be reproducibly induced in the anesthetized chronic AV-block (CAVB) dog by infusion of the I-blocker dofetilide. Earlier studies showed that...
4.
van Weperen V, Vaseghi M
Front Neurosci
. 2023 Jun;
17:1192188.
PMID: 37351426
The meticulous control of cardiac sympathetic and parasympathetic tone regulates all facets of cardiac function. This precise calibration of cardiac efferent innervation is dependent on sensory information that is relayed...
5.
van Weperen V, Ripplinger C, Vaseghi M
Clin Auton Res
. 2023 May;
33(4):491-517.
PMID: 37166736
Purpose: Cardiac autonomic dysfunction is one of the main pillars of cardiovascular pathophysiology. The purpose of this review is to provide an overview of the current state of the art...
6.
van Weperen V, Ter Horst I, Dunnink A, Bossu A, Salden O, Beekman H, et al.
Europace
. 2022 Sep;
25(2):707-715.
PMID: 36125234
Aims: Altered ventricular activation (AVA) causes intraventricular mechanical dyssynchrony (MD) and impedes contraction, promoting pro-arrhythmic electrical remodelling in the chronic atrioventricular block (CAVB) dog. We aimed to study arrhythmogenic and...
7.
Van Bavel J, Beekman H, van Weperen V, van der Linde H, van der Heyden M, Vos M
Eur J Pharmacol
. 2022 Aug;
932:175218.
PMID: 36007604
Introduction: Impaired I induced by drugs or due to a KCNQ1 mutation, diagnosed as long QT syndrome type 1 (LQT1) prolongs the QT interval and predisposes the heart to Torsade...
8.
van Weperen V, Vos M, Ajijola O
Clin Auton Res
. 2021 Sep;
31(6):659-676.
PMID: 34591191
Purpose: This review aimed to provide a complete overview of the current stance and recent developments in antiarrhythmic neuromodulatory interventions, focusing on lifethreatening vetricular arrhythmias. Methods: Both preclinical studies and...
9.
Smoczynska A, Aarnink E, Dunnink A, Bossu A, van Weperen V, Meijborg V, et al.
Am J Physiol Heart Circ Physiol
. 2021 Aug;
321(3):H569-H576.
PMID: 34355987
Ventricular arrhythmias, consisting of single ectopic beats (sEB), multiple EB (mEB), and torsades de pointes (TdP, defined as ≥5 beats with QRS vector twisting around isoelectric line) can be induced...
10.
van Weperen V, Dunnink A, Bossu A, Beekman J, Meijborg V, de Bakker J, et al.
Front Physiol
. 2021 May;
12:642083.
PMID: 33981248
Introduction: Torsade de pointes arrhythmias (TdP) in the chronic atrioventricular block (CAVB) dog model result from proarrhythmic factors, which trigger TdP and/or reinforce the arrhythmic substrate. This study investigated electrophysiological...