Valerie Trimble
Overview
Explore the profile of Valerie Trimble including associated specialties, affiliations and a list of published articles.
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6
Citations
366
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0
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Recent Articles
1.
Dominguez Castro P, Harkin G, Hussey M, Christopher B, Kiat C, Chin J, et al.
United European Gastroenterol J
. 2020 Mar;
8(2):148-156.
PMID: 32213077
Background: Coeliac disease (CD) is associated with an increased risk of other immune-mediated conditions. : To investigate the prevalence of coexistent immune-mediated diseases in CD patients, and changes in the...
2.
Dominguez Castro P, Harkin G, Hussey M, Christopher B, Kiat C, Chin J, et al.
Clin Gastroenterol Hepatol
. 2017 Jan;
15(6):864-871.e3.
PMID: 28043932
Background & Aims: Celiac disease is an immune-mediated enteropathy characterized with high heterogeneity in presentation among genetically predisposed individuals. In recent years, a change in the phenotypic presentation of celiac...
3.
Quinn E, Coleman C, Molloy B, Dominguez Castro P, Cormican P, Trimble V, et al.
PLoS One
. 2015 Oct;
10(10):e0140049.
PMID: 26444573
Genetic studies have to date identified 43 genome wide significant coeliac disease susceptibility (CD) loci comprising over 70 candidate genes. However, how altered regulation of such disease associated genes contributes...
4.
Coleman C, Quinn E, Ryan A, Conroy J, Trimble V, Mahmud N, et al.
Eur J Hum Genet
. 2015 Apr;
24(2):291-7.
PMID: 25920553
Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It has an estimated prevalence of approximately 1% in European populations. Specific HLA-DQA1 and HLA-DQB1 alleles...
5.
Brophy K, Ryan A, Turner G, Trimble V, Patel K, OMorain C, et al.
BMC Med Genet
. 2010 May;
11:76.
PMID: 20478055
Background: Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with...
6.
Hunt K, Zhernakova A, Turner G, Heap G, Franke L, Bruinenberg M, et al.
Nat Genet
. 2008 Mar;
40(4):395-402.
PMID: 18311140
Our genome-wide association study of celiac disease previously identified risk variants in the IL2-IL21 region. To identify additional risk variants, we genotyped 1,020 of the most strongly associated non-HLA markers...