Valerie P Wright
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Explore the profile of Valerie P Wright including associated specialties, affiliations and a list of published articles.
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10
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289
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Recent Articles
1.
Shantaram D, Hoyd R, Blaszczak A, Antwi L, Jalilvand A, Wright V, et al.
Nat Commun
. 2024 Jun;
15(1):5434.
PMID: 38937454
Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains more neutrophils than in those without obesity...
2.
Blaszczak A, Quiroga D, Jalilvand A, Torres Matias G, Wright V, Liu J, et al.
Surg Oncol
. 2021 Sep;
39:101659.
PMID: 34534729
Background: Adipose tissue has emerged as an important window into cancer pathophysiology, revealing potential targets for novel therapeutic interventions. The goal of this study was to compare the breast adipose...
3.
Blaszczak A, Bernier M, Wright V, Gebhardt G, Anandani K, Liu J, et al.
Immunometabolism
. 2020 Aug;
2(3).
PMID: 32774894
Background: Obesity is characterized by visceral adipose tissue (AT) inflammation. Immunosuppressive regulatory T cells (Tregs), phagocytic M2-like macrophages, and innate lymphoid cells type 2 (ILC2) control lean AT inflammation to...
4.
Blaszczak A, Wright V, Anandani K, Liu J, Jalilvand A, Bergin S, et al.
J Immunol
. 2019 Mar;
202(8):2451-2459.
PMID: 30850480
Macrophages, B cells, and adipocytes are among the adipose tissue (AT) APCs that differentiate and activate naive CD4 T cells. Mice with adipocyte loss of MHC class II (MHC II)...
5.
Blaszczak A, Jalilvand A, Liu J, Wright V, Suzo A, Needleman B, et al.
J Diabetes Res
. 2019 Feb;
2019:8124563.
PMID: 30719456
Obesity is associated with a state of chronic low-grade inflammation both systemically and within specific tissues, including adipose tissue (AT). In murine models of obesity, there is a shift in...
6.
Dakhlallah D, Batte K, Wang Y, Cantemir-Stone C, Yan P, Nuovo G, et al.
Am J Respir Crit Care Med
. 2013 Jan;
187(4):397-405.
PMID: 23306545
Rationale: Idiopathic pulmonary fibrosis (IPF) is a disease of progressive lung fibrosis with a high mortality rate. In organ repair and remodeling, epigenetic events are important. MicroRNAs (miRNAs) regulate gene...
7.
Wright V, Reiser P, Clanton T
J Physiol
. 2009 Oct;
587(Pt 23):5767-81.
PMID: 19841000
Skeletal muscles produce transient reactive oxygen species (ROS) in response to intense stimulation, disuse atrophy, heat stress, hypoxia, osmotic stress, stretch and cell receptor activation. The physiological significance is not...
8.
Oliver S, Wright V, Parinandi N, Clanton T
Am J Physiol Regul Integr Comp Physiol
. 2008 Sep;
295(5):R1695-705.
PMID: 18768765
Mechanisms for the loss of muscle contractile function in hyperthermia are poorly understood. This study identified the critical temperature, resulting in a loss of contractile function in isolated diaphragm (thermal...
9.
Zuo L, Christofi F, Wright V, Bao S, Clanton T
J Appl Physiol (1985)
. 2004 Apr;
97(2):661-8.
PMID: 15107407
Superoxide anion radical (O(2)(*-)) is released from skeletal muscle at rest and is particularly elevated during conditions of heat stress (42 degrees C). Previous studies have shown that in isolated...
10.
Zuo L, Pasniciuc S, Wright V, Merola A, Clanton T
Antioxid Redox Signal
. 2003 Oct;
5(5):667-75.
PMID: 14580324
Isolated diaphragm releases low levels of superoxide (O2*-) at rest and much higher levels during heat stress. The molecular source is unknown. The hypothesis was tested that heat stress stimulates...