Valentina Cazzetta
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Explore the profile of Valentina Cazzetta including associated specialties, affiliations and a list of published articles.
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10
Citations
128
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Recent Articles
1.
Terzoli S, Marzano P, Cazzetta V, Piazza R, Sandrock I, Ravens S, et al.
NPJ Vaccines
. 2024 Mar;
9(1):63.
PMID: 38509155
γδ T cells provide rapid cellular immunity against pathogens. Here, we conducted matched single-cell RNA-sequencing and γδ-TCR-sequencing to delineate the molecular changes in γδ T cells during a longitudinal study...
2.
Marzano P, Balin S, Terzoli S, Della Bella S, Cazzetta V, Piazza R, et al.
Front Immunol
. 2023 Aug;
14:1208662.
PMID: 37564651
Introduction: Higher frequencies of mucosal-associated invariant T (MAIT) cells were associated with an increased adaptive response to mRNA SARS-CoV-2 vaccine, however, the mechanistic insights into this relationship are unknown. In...
3.
Bernson E, Huhn O, Karlsson V, Hawkes D, Lycke M, Cazzetta V, et al.
Cancers (Basel)
. 2023 Jul;
15(13).
PMID: 37444472
Women with ovarian cancer have limited therapy options, with immunotherapy being unsatisfactory for a large group of patients. Tumor cells spread from the ovary or the fallopian tube into the...
4.
Cazzetta V, Depierreux D, Colucci F, Mikulak J, Mavilio D
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831606
Immune regulation has revolutionized cancer treatment with the introduction of T-cell-targeted immune checkpoint inhibitors (ICIs). This successful immunotherapy has led to a more complete view of cancer that now considers...
5.
Bruni E, Cimino M, Donadon M, Carriero R, Terzoli S, Piazza R, et al.
J Immunother Cancer
. 2022 Jul;
10(7).
PMID: 35863820
Background: More than 50% of all patients with colorectal cancer (CRC) develop liver metastases (CLM), a clinical condition characterized by poor prognosis and lack of reliable prognostic markers. Vδ1 cells...
6.
Cazzetta V, Bruni E, Terzoli S, Carenza C, Franzese S, Piazza R, et al.
Cell Rep
. 2021 Oct;
37(3):109871.
PMID: 34686325
Human Vδ2 cells are innate-like γδ T effectors performing potent immune surveillance against tumors. The constitutive expression of NKG2A identifies a subset of Vδ2 T cells licensed with an intrinsic...
7.
Cazzetta V, Franzese S, Carenza C, Della Bella S, Mikulak J, Mavilio D
Cancers (Basel)
. 2021 Jun;
13(9).
PMID: 34062821
Natural killer (NK) and dendritic cells (DCs) are innate immune cells that play a crucial role in anti-tumor immunity. NK cells kill tumor cells through direct cytotoxicity and cytokine secretion....
8.
Polidoro M, Mikulak J, Cazzetta V, Lleo A, Mavilio D, Torzilli G, et al.
World J Gastroenterol
. 2020 Sep;
26(33):4900-4918.
PMID: 32952338
In the last years, several studies have been focused on elucidate the role of tumor microenvironment (TME) in cancer development and progression. Within TME, cells from adaptive and innate immune...
9.
Valsecchi M, Cazzetta V, Oriolo F, Lan X, Piazza R, Saleem M, et al.
Glycoconj J
. 2020 Sep;
37(6):729-744.
PMID: 32915357
Apolipoprotein L1 (APOL1) wild type (G0) plays a role in the metabolism of sphingolipids, glycosphingolipids, sphingomyelin and ceramide, which constitute bioactive components of the lipid rafts (DRM). We asked whether...
10.
Bruni E, Cazzetta V, Donadon M, Cimino M, Torzilli G, Spata G, et al.
J Immunother Cancer
. 2019 Dec;
7(1):347.
PMID: 31829255
Human (gamma delta) γδ T cells are unconventional innate-like lymphocytes displaying a broad array of anti-tumor activities with promising perspectives in cancer immunotherapy. In this context, Vδ2 T cells represent...