Vajira H W Dissanayake
Overview
Explore the profile of Vajira H W Dissanayake including associated specialties, affiliations and a list of published articles.
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83
Citations
624
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Recent Articles
1.
Arachchige N, Sirisena N, De Silva S, Senathilake K, Faizan M, Dissanayake V
Hum Genomics
. 2025 Feb;
19(1):12.
PMID: 39940038
Background: Next-generation sequencing (NGS)-based testing is a cost-effective method for identifying pathogenic germline genetic variations in cancer-predisposing genes in hereditary breast cancer. However, many of the variants detected through NGS...
2.
Ranasinghe P, Jeyapragasam H, Sirisena N, Hendalage D, Dissanayake V
BMC Infect Dis
. 2025 Feb;
25(1):153.
PMID: 39893405
Background: Anti-infective medicines are crucial for treating infections, but improper dosing can cause toxicity, resistance and treatment failure. Pharmacogenomics can address genetic variations affecting drug efficacy and safety. Despite the...
3.
Car J, Ong Q, Erlikh Fox T, Leightley D, Kemp S, Svab I, et al.
JAMA Netw Open
. 2025 Jan;
8(1):e2453131.
PMID: 39888625
Importance: Rapid digitalization of health care and a dearth of digital health education for medical students and junior physicians worldwide means there is an imperative for more training in this...
4.
Ranasinghe P, Gunarathna P, Jeyapragasam H, Sirisena N, Hendalage D, Dissanayake V
Pharmacogenomics
. 2025 Jan;
25(16-18):657-660.
PMID: 39809701
Aims: Clopidogrel exhibits substantial variability in therapeutic response, largely contributed by genetic factors. The pharmacogenomic variants data on clopidogrel metabolism in South Asians have been sparsely studied. This study explores...
5.
Ranasinghe P, Liyanage C, Sirisena N, Liyanage S, Priyadarshani C, Hendalage D, et al.
Hum Genomics
. 2024 Sep;
18(1):107.
PMID: 39334333
Background: Immunomodulators are important for management of autoimmune diseases and hematological malignancies. Significant inter-individual variation in drug response/reactions exists due to genetic polymorphisms. We describe frequency of identified genetic polymorphisms...
6.
Gunawardena K, Praveenan S, Dissanayake V, Ratnayake P
J Med Case Rep
. 2024 Sep;
18(1):420.
PMID: 39252049
Background: Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes and nemaline myopathy are two rare genetic conditions. We report the first case reported in world literature with coexistence of both these...
7.
Ranasinghe P, Sirisena N, Vishnukanthan T, Ariadurai J, Thilakarathne S, Priyadarshani C, et al.
BMC Med Genomics
. 2024 May;
17(1):143.
PMID: 38789983
Background: Therapy with anti-cancer drugs remain the cornerstone of treating cancer. The effectiveness and safety of anti-cancer drugs vary significantly among individuals due to genetic factors influencing the drug response...
8.
Kolambage Y, Walpita Y, Liyanage U, Dayaratne B, Dissanayake V
Orphanet J Rare Dis
. 2023 Sep;
18(1):279.
PMID: 37684696
Background: Skeletal dysplasias are a diverse group of rare disorders in the chondro-osseous tissue that can have a significant impact on patient's functionality. The worldwide prevalence of skeletal dysplasias at...
9.
Ranasinghe G, Sovis R, Shellvacumar S, Dissanayake V
Eur Heart J Case Rep
. 2023 Sep;
7(9):ytad419.
PMID: 37662584
Background: Spontaneous coronary artery dissection (SCAD) is increasingly diagnosed as one of the infrequent causes of acute coronary syndrome. Almost no cause was identified in half of the cases. Here,...
10.
Ralapanawe M, Gajaweera S, Karunaratne N, Dissanayake V, Price M, Melo P, et al.
Sci Rep
. 2023 Jun;
13(1):10099.
PMID: 37344525
No abstract available.