V Verhoef
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Explore the profile of V Verhoef including associated specialties, affiliations and a list of published articles.
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11
Citations
44
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Recent Articles
1.
Volpe D, Du D, Verhoef V, Murphy Jr M
Pathobiology
. 1993 Jan;
61(2):77-82.
PMID: 8216829
Mycobacterial infection is a common complication of acquired immunodeficiency syndrome (AIDS) frequently requiring antimycobacterial medication. It was of interest to determine if one such agent, rifabutin, could be tolerated by...
2.
Sarup J, Johnson M, Verhoef V, Fridland A
Biochem Pharmacol
. 1989 Aug;
38(16):2601-7.
PMID: 2548513
The kinetics and regulation of nucleoside phosphorylation by highly purified human deoxycytidine kinase from leukemic lymphoblasts were studied. The phosphorylation of purine nucleosides by this enzyme showed sensitivity to the...
3.
Fridland A, Verhoef V
Semin Oncol
. 1987 Jun;
14(2 Suppl 1):262-8.
PMID: 3035721
No abstract available.
4.
Verhoef V, Ashmun R, Fridland A
Anticancer Res
. 1986 Sep;
6(5):1117-21.
PMID: 2879509
We used human lymphocytes from the peripheral blood of normal individuals to compare the cytolytic actions of 2-chloro-2'-deoxyadenosine (2-Cl-dAdo) and 9-beta-D-arabinofuranosylguanine (ara-G). Membrane integrity was ascertained by flow cytometric quantification...
5.
Fridland A, Verhoef V
Proc Soc Exp Biol Med
. 1985 Sep;
179(4):456-62.
PMID: 2991939
The selective toxicity of purine deoxynucleosides against lymphoid cells appears to be mediated by a preferential accumulation of the corresponding triphosphates in these cells. We report a study of the...
6.
Verhoef V, Fridland A
Cancer Res
. 1985 Aug;
45(8):3646-50.
PMID: 2410098
Purine analogues are potentially useful agents for selective chemotherapy of lymphoproliferative diseases. We compared the toxic effects of various arabinonucleosides against eight human T- and B-lymphoblastoid lines. The arabinosides of...
7.
Verhoef V, Germain G, Fridland A
Exp Cell Res
. 1983 Nov;
149(1):37-44.
PMID: 6416875
Mammalian cells have enzymes that deaminate adenosine to inosine, which can readily be phosphorolysed to hypoxanthine. They do not, however, possess enzymes to form adenine by the cleavage of adenosine....
8.
Chwang T, Fridland A, Verhoef V
Biochem Pharmacol
. 1983 Sep;
32(17):2943-6.
PMID: 6577862
No abstract available.
9.
Verhoef V, Sarup J, Fridland A
Cancer Res
. 1981 Nov;
41(11 Pt 1):4478-83.
PMID: 6272978
The biochemical basis of cellular resistance to 9-beta-D-arabinofuranosyladenine (ara-A) and its natural purine derivative, deoxyadenosine, was investigated with two mutants of cultured human T-lymphoblastoid CCRF-CEM cells. One mutant that lacked...
10.
HENDERSON J, Zombor G, Fraser J, McCoy E, Verhoef V, Morris A
Can J Biochem
. 1977 Apr;
55(4):359-64.
PMID: 15708
Measurements of rates of inosinate synthesis from radioactive hypoxanthine by human erythrocytes show a large degree of individual variation. Rates of inosinate synthesis also vary with the pH and phosphate...