V Nathan Subramaniam
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Explore the profile of V Nathan Subramaniam including associated specialties, affiliations and a list of published articles.
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96
Citations
1485
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Recent Articles
1.
Prasadam I, Schrobback K, Kranz-Rudolph B, Fischer N, Sonar Y, Sun A, et al.
J Mol Med (Berl)
. 2024 Nov;
103(1):73-86.
PMID: 39531048
Osteoarthritis (OA) is a prevalent degenerative joint disease affecting over 530 million individuals worldwide. Recent studies suggest a potential link between iron overload, a condition characterised by the excessive accumulation...
2.
Huang G, Wallace D, Powell E, Rahman T, Clark P, Subramaniam V
Biomedicines
. 2023 Oct;
11(10).
PMID: 37893185
Non-alcoholic fatty liver disease (NAFLD) describes a steatotic (or fatty) liver occurring as a consequence of a combination of metabolic, environmental, and genetic factors, in the absence of significant alcohol...
3.
Goncalves Monteiro D, Rishi G, Gorman D, Burnet G, Aliyanto R, Rosengren K, et al.
Molecules
. 2022 Oct;
27(19).
PMID: 36235117
The protein HFE (homeostatic iron regulator) is a key regulator of iron metabolism, and mutations in HFE underlie the most frequent form of hereditary haemochromatosis (HH-type I). Studies have shown...
4.
Rishi G, Huang G, Subramaniam V
Int J Biochem Cell Biol
. 2021 Oct;
141:106094.
PMID: 34628027
Iron is an essential element for virtually all living things. Body iron levels are tightly controlled as both increased iron levels and iron deficiency are associated with many clinical conditions....
5.
Baas F, Rishi G, Swinkels D, Subramaniam V
Clin Chem
. 2021 Aug;
67(10):1324-1341.
PMID: 34402502
Background: Hereditary hemochromatosis (HH) is a genetic disease, leading to iron accumulation and possible organ damage. Patients are usually homozygous for p. Cys282Tyr in the homeostatic iron regulator gene but...
6.
Hawula Z, Secondes E, Wallace D, Rishi G, Subramaniam V
Biosci Rep
. 2021 Jun;
41(7).
PMID: 34156073
The flavonol rutin has been shown to possess antioxidant and iron chelating properties in vitro and in vivo. These dual properties are beneficial as therapeutic options to reduce iron accumulation...
7.
Hawula Z, Davis R, Wallace D, Rishi G, Subramaniam V
Biometals
. 2021 Apr;
34(4):855-866.
PMID: 33913062
Iron is an essential component for multiple biological processes. Its regulation within the body is thus tightly controlled. Dysregulation of iron levels within the body can result in several disorders...
8.
Crawford D, Ross D, Jaskowski L, Burke L, Britton L, Musgrave N, et al.
Biochim Biophys Acta Mol Basis Dis
. 2021 Apr;
1867(7):166142.
PMID: 33839281
Background & Aims: Iron has been proposed as influencing the progression of liver disease in subjects with non-alcoholic fatty liver disease (NAFLD). We have previously shown that, in the Hfe...
9.
Rishi G, Subramaniam V
Adv Protein Chem Struct Biol
. 2021 Jan;
123:1-16.
PMID: 33485480
Iron, the most common metal in the earth, is also an essential component for almost all living organisms. While these organisms require iron for many biological processes, too much or...
10.
Milanese C, Gabriels S, Barnhoorn S, Cerri S, Ulusoy A, Gornati S, et al.
Cell Death Differ
. 2020 Dec;
28(5):1720-1732.
PMID: 33323945
Alterations in the metabolism of iron and its accumulation in the substantia nigra pars compacta accompany the pathogenesis of Parkinson's disease (PD). Changes in iron homeostasis also occur during aging,...