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V M Keivens

Explore the profile of V M Keivens including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 249
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Recent Articles
1.
Ill C, Gonzales J, Houtz E, Ludwig J, Melcher E, Hale J, et al.
Protein Eng . 1997 Aug; 10(8):949-57. PMID: 9415445
The complementarity-determining regions (CDRs) of a human kappa light chain were replaced with CDRs from a murine gamma-1 heavy chain and, by use of molecular modeling, key heavy chain framework...
2.
Hughes P, Renshaw M, Pfaff M, Forsyth J, Keivens V, Schwartz M, et al.
Cell . 1997 Feb; 88(4):521-30. PMID: 9038343
Rapid modulation of ligand binding affinity ("activation") is a central property of the integrin cell adhesion receptors. Using a screen for suppressors of integrin activation, we identified the small GTP-binding...
3.
Wu C, Keivens V, OToole T, McDonald J, Ginsberg M
Cell . 1995 Dec; 83(5):715-24. PMID: 8521488
Fibronectin (Fn) matrices are vital to vertebrate development and wound healing and modulate tumorigenesis. We used a recombinant Fn-binding integrin alpha IIb beta3, to define rules for integrin-initiated Fn matrix...
4.
Ill C, Keivens V, Hale J, Nakamura K, Jue R, Cheng S, et al.
Biophys J . 1993 Mar; 64(3):919-24. PMID: 8471734
An antibody (IgG1) was designed for oriented adherence to a metal-containing surface. This was achieved by adding a metal-chelating peptide, (CP = His-Trp-His-His-His-Pro), to the COOH-terminus of the heavy chain...