V L Bonato
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Explore the profile of V L Bonato including associated specialties, affiliations and a list of published articles.
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11
Citations
250
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Recent Articles
1.
Cavalcanti-Neto M, Prado R, Pineros A, Sergio C, Bertolini T, Gembre A, et al.
Tuberculosis (Edinb)
. 2018 Dec;
113:1-9.
PMID: 30514491
Given the impossibility to study the lung immune response during Mycobacterium tuberculosis-latent infection, and consequently, the mechanisms that control the bacterial load, it is reasonable to determine the activation of...
2.
Downmodulation of CD18 and CD86 on macrophages and VLA-4 on lymphocytes in experimental tuberculosis
Bonato V, Medeiros A, Lima V, Dias A, Faccioliti L, Silva C
Scand J Immunol
. 2002 Mar;
54(6):564-73.
PMID: 11902331
Development and evaluation of new vaccines and immunotherapy against tuberculosis demand a better understanding of the immune mechanisms in this disease. Costimulatory signals and intercellular contact seem to be pivotal...
3.
Lima V, Bonato V, Lima K, dos Santos S, Santos R, Goncalves E, et al.
Infect Immun
. 2001 Aug;
69(9):5305-12.
PMID: 11500399
Mice treated with viable Mycobacterium tuberculosis with no glycolipid trehalose dimycolate (TDM) on the outer cell wall (delipidated M. tuberculosis) by intraperitoneal or intratracheal inoculation presented an intense recruitment of...
4.
Lima K, Bonato V, Faccioli L, Brandao I, dos Santos S, Leao S, et al.
Vaccine
. 2001 May;
19(25-26):3518-25.
PMID: 11348719
The way to deliver antigens and cellular requirements for long-lasting protection against tuberculosis are not known. Immunizations with mycobacterial 65 kDa heat shock protein (hsp65) expressed from J774-hsp65 cells (antigen-presenting...
5.
Silva C, Bonato V, Lima K, Faccioli L, Sartori A, De Souza A, et al.
FEMS Microbiol Lett
. 2001 Apr;
197(1):11-8.
PMID: 11287139
How the immune system kills Mycobacterium tuberculosis is still a puzzle. The classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent...
6.
Silva C, Bonato V, Lima V, Faccioli L, Leao S
Immunology
. 1999 Aug;
97(4):573-81.
PMID: 10457209
The memory/activated T cells, which mediate the long-lived host response against tuberculosis, in mice immunized with either bacillus Calmette-Guérin (BCG) or mycobacterium heat-shock protein 65 (hsp 65) antigen expressed from...
7.
Lowrie D, Tascon R, Bonato V, Lima V, Faccioli L, Stavropoulos E, et al.
Nature
. 1999 Jul;
400(6741):269-71.
PMID: 10421369
Mycobacterium tuberculosis continues to kill about 3 million people every year, more than any other single infectious agent. This is attributed primarily to an inadequate immune response towards infecting bacteria,...
8.
Silva C, Bonato V, Lima V
Braz J Med Biol Res
. 1999 May;
32(2):231-4.
PMID: 10347759
Over the last few years, some of our experiments in which mycobacterial antigens were presented to the immune system as if they were viral antigens have had a significant impact...
9.
Silva C, Portaro F, Bonato V, de Camargo A, Ferro E
Biochem Biophys Res Commun
. 1999 Mar;
255(3):591-5.
PMID: 10049755
The initial processing of antigens leading to major histocompatibility complex (MHC) class I antigenic peptides is carried out by the proteasome. However, how the final epitopes are generated and protected...
10.
Bonato V, Lima V, Tascon R, Lowrie D, Silva C
Infect Immun
. 1998 Jan;
66(1):169-75.
PMID: 9423854
Immunization by intramuscular injection of plasmid DNA expressing mycobacterial 65-kDa heat shock protein (hsp65) protects mice against challenge with virulent Mycobacterium tuberculosis H37Rv. During infection or after immunization, CD4+/CD8- and...