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V Jaks

Explore the profile of V Jaks including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 141
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Recent Articles
1.
Pook M, Tamming L, Padari K, Tiido T, Maimets T, Patarroyo M, et al.
J Thromb Haemost . 2014 Jan; 12(4):519-27. PMID: 24450402
Background: Blood platelets secrete upon activation of laminins 411/421 and 511/521, large adhesive proteins mainly found in the basement membranes of blood vessels and other tissues. At present, the subcellular...
2.
Chari N, Romano R, Koster M, Jaks V, Roop D, Flores E, et al.
Cell Death Differ . 2013 May; 20(8):1080-8. PMID: 23686138
Deregulation of the hedgehog (HH) pathway results in overexpression of the GLI target BCL2 and is an initiating event in specific tumor types including basal cell carcinoma of the skin....
3.
Sonkoly E, Loven J, Xu N, Meisgen F, Wei T, Brodin P, et al.
Oncogenesis . 2013 Apr; 1:e3. PMID: 23552555
Basal cell carcinoma (BCC) of the skin represents the most common malignancy in humans. MicroRNAs (miRNAs), small regulatory RNAs with pleiotropic function, are commonly misregulated in cancer. Here we identify...
4.
Barker N, Van Es J, Jaks V, Kasper M, Snippert H, Toftgard R, et al.
Cold Spring Harb Symp Quant Biol . 2009 May; 73:351-6. PMID: 19478326
The intestinal epithelium and the hair follicle represent examples of rapidly self-renewing tissue in adult mammals. We have recently identified a novel stem cell gene Lgr5 expressed in multiple adult...
5.
Jaks V, Joers A, Kristjuhan A, Maimets T
Oncogene . 2001 Apr; 20(10):1212-9. PMID: 11313865
In this study we characterize the connections between p53-dependent G1 cell cycle arrest, transcriptional activation of the protein and the increase of its intracellular steady-state concentration. Several cell lines expressing...
6.
Kristjuhan A, Jaks V, Rimm I, Tooming T, Maimets T
Oncogene . 1998 Jun; 16(18):2413-8. PMID: 9620560
We have previously shown that transactivation by tumor suppressor protein p53 can be inhibited in vivo at elevated protein concentrations. In this study we characterize the structural requirements of this...