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V Haroutunian

Explore the profile of V Haroutunian including associated specialties, affiliations and a list of published articles. Areas
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Articles 123
Citations 4482
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Recent Articles
1.
Katsel P, Roussos P, Beeri M, Gama-Sosa M, Gandy S, Khan S, et al.
PLoS One . 2018 Nov; 13(11):e0206547. PMID: 30383799
A large body of literature links risk of cognitive decline, mild cognitive impairment (MCI) and dementia with Type 2 Diabetes (T2D) or pre-diabetes. Accumulating evidence implicates a close relationship between...
2.
McCullumsmith R, ODonovan S, Drummond J, Benesh F, Simmons M, Roberts R, et al.
Mol Psychiatry . 2016 May; 21(6):723. PMID: 27198660
No abstract available.
3.
Fa M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons M, et al.
Sci Rep . 2016 Jan; 6:19393. PMID: 26786552
Non-fibrillar soluble oligomeric forms of amyloid-β peptide (oAβ) and tau proteins are likely to play a major role in Alzheimer's disease (AD). The prevailing hypothesis on the disease etiopathogenesis is...
4.
Readhead B, Haure-Mirande J, Zhang B, Haroutunian V, Gandy S, Schadt E, et al.
Mol Psychiatry . 2016 Jan; 21(8):1153-4. PMID: 26782051
No abstract available.
5.
Readhead B, Haure-Mirande J, Zhang B, Haroutunian V, Gandy S, Schadt E, et al.
Mol Psychiatry . 2015 Nov; 21(8):1099-111. PMID: 26552589
Identification and characterization of molecular mechanisms that connect genetic risk factors to initiation and evolution of disease pathophysiology represent major goals and opportunities for improving therapeutic and diagnostic outcomes in...
6.
McCullumsmith R, ODonovan S, Drummond J, Benesh F, Simmons M, Roberts R, et al.
Mol Psychiatry . 2015 Sep; 21(6):823-30. PMID: 26416546
Excitatory amino-acid transporters (EAATs) bind and transport glutamate, limiting spillover from synapses due to their dense perisynaptic expression primarily on astroglia. Converging evidence suggests that abnormalities in the astroglial glutamate...
7.
Mueller T, Remedies C, Haroutunian V, Meador-Woodruff J
Transl Psychiatry . 2015 Aug; 5:e612. PMID: 26241350
Inhibitory neurotransmission is primarily mediated by γ-aminobutyric acid (GABA) activating synaptic GABA type A receptors (GABA(A)R). In schizophrenia, presynaptic GABAergic signaling deficits are among the most replicated findings; however, postsynaptic...
8.
ODonovan S, Hasselfeld K, Bauer D, Simmons M, Roussos P, Haroutunian V, et al.
Transl Psychiatry . 2015 Jun; 5:e579. PMID: 26057049
Dysregulation of the glutamate transporters EAAT1 and EAAT2 and their isoforms have been implicated in schizophrenia. EAAT1 and EAAT2 expression has been studied in different brain regions but the prevalence...
9.
Hertzberg L, Katsel P, Roussos P, Haroutunian V, Domany E
Schizophr Res . 2015 Feb; 164(1-3):92-9. PMID: 25702973
The number of Genome Wide Association Studies (GWAS) of schizophrenia is rapidly growing. However, the small effect of individual genes limits the number of reliably implicated genes, which are too...
10.
Haroutunian V, Katsel P, Roussos P, Davis K, Altshuler L, Bartzokis G
Glia . 2014 Jul; 62(11):1856-77. PMID: 25056210
Historically, the human brain has been conceptually segregated from the periphery and further dichotomized into gray matter (GM) and white matter (WM) based on the whitish appearance of the exceptionally...