V Gurewich
Overview
Explore the profile of V Gurewich including associated specialties, affiliations and a list of published articles.
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Articles
140
Citations
680
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Recent Articles
1.
Gurewich V, Pannell R
J Thromb Haemost
. 2017 Aug;
15(10):2080-2081.
PMID: 28799246
No abstract available.
2.
Pannell R, Li S, Gurewich V
J Thromb Thrombolysis
. 2017 Jun;
44(2):210-215.
PMID: 28600623
Thrombolysis with tissue plasminogen activator (tPA) has been a disappointment and has now been replaced by an endovascular procedure whenever possible. Nevertheless, thrombolysis remains the only means by which circulation...
3.
4.
Gurewich V, Pannell R
J Thromb Haemost
. 2016 Jun;
14(9):1899-900.
PMID: 27343843
No abstract available.
5.
Pannell R, Kung W, Gurewich V
J Thromb Haemost
. 2007 Apr;
5(5):1047-54.
PMID: 17459007
Background: Prourokinase (prouPA) is unstable in plasma at therapeutic concentrations. A mutant form, M5, made more stable by reducing its intrinsic activity was therefore developed. Activation to two-chain M5 (tcM5)...
6.
Gurewich V, Pannell R, Simmons-Byrd A, Sarmientos P, Liu J, Badylak S
J Thromb Haemost
. 2006 Jul;
4(7):1559-65.
PMID: 16839354
Background: A single site mutant (M5) of prourokinase (proUK) was developed to make proUK less vulnerable to spontaneous activation in plasma. This was a problem that seriously compromised proUK in...
7.
Camoin-Jau L, Pannell R, Anfosso F, Bardin N, Sabatier F, Sampol J, et al.
Thromb Haemost
. 2002 Sep;
88(3):517-23.
PMID: 12353084
Adhesion of platelets to endothelium has been shown to induce important changes in endothelial properties. In this study, we examined the effect of platelet-endothelial cell interactions on the expression of...
8.
Li C, Zhang J, Jiang Y, Gurewich V, Chen Y, Liu J
Thromb Res
. 2001 Oct;
103(3):221-32.
PMID: 11672584
Signal transduction by urokinase-type plasminogen activator (u-PA) bound to its cell receptor has been well established. In the present study, we found, for the first time to our knowledge, that...
9.
Wang P, Zhang J, Sun Z, Chen Y, Gurewich V, Liu J
Thromb Res
. 2001 Jan;
100(5):461-7.
PMID: 11150590
The enzymatic and fibrinolytic properties of glycosylated and nonglycosylated recombinant human pro-urokinase (pro-UK) produced in yeast Pichia pastoris were characterized and compared with those of Escherichia coli and mammalian cell-derived...
10.
Gurewich V
Blood Coagul Fibrinolysis
. 2000 Aug;
11(5):401-8.
PMID: 10937799
There has been a recent decline in interest in fibrinolysis, suggesting that its physiological basis is sufficiently understood and that therapeutic thrombolysis has reached its limit. The importance of the...