V A Levin
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Explore the profile of V A Levin including associated specialties, affiliations and a list of published articles.
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243
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5530
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Recent Articles
1.
Levin V, Jiang X, Kagan R
Osteoporos Int
. 2018 Mar;
29(5):1049-1055.
PMID: 29520604
Menopause predisposes women to osteoporosis due to declining estrogen levels. This results in a decrease in bone mineral density (BMD) and an increase in fractures. Osteoporotic fractures lead to substantial...
2.
Vartanyan E, Tsaturova K, Devyatova E, Mikhaylyukova A, Levin V, Petuhova N, et al.
Gynecol Endocrinol
. 2017 Dec;
33(sup1):8-11.
PMID: 29264980
Inositol therapy is aimed at improving the quality of oocytes during preconception care in patients with polycystic ovarian syndrome (PCOS), a cause of infertility and reproductive dysfunction. The objectives of...
3.
Levin V, Dolginow D, Landahl H, Yorke C, Csejtey J
Pharm Res
. 2013 Nov;
1(6):259-66.
PMID: 24277359
We have used modified standard methods and derived new formulae to quantitate cell permeability (P), cell/media partitioning (λ), and intracellular sequestration or binding rate constants (m) for cultured S49 murine...
4.
Pulst S, Levin V, Deen D
Pharm Res
. 2013 Nov;
3(5):302-6.
PMID: 24271715
Dibromodulcitol (DBD) is a halogenated hexitol active against animal and human brain tumors in vivo. In aqueous solution, DBD is transformed to products with different cytotoxicities. We studied the in...
5.
Groves M, Puduvalli V, Gilbert M, Levin V, Conrad C, Liu V, et al.
Br J Cancer
. 2009 Aug;
101(4):615-20.
PMID: 19672263
Background: Because of the poor outcomes for patients with recurrent glioblastoma multiforme (GBM), and some laboratory and clinical evidence of efficacy using interferon in GBM, we assessed the toxicity and...
6.
Shantz L, Levin V
Amino Acids
. 2007 Apr;
33(2):213-23.
PMID: 17443268
The activity of ornithine decarboxylase (ODC(1)), the first enzyme in polyamine biosynthesis, is induced during carcinogenesis by a variety of oncogenic stimuli. Intracellular levels of ODC and the polyamines are...
7.
Levin V, Giglio P, Puduvalli V, Jochec J, Groves M, Yung W, et al.
J Neurooncol
. 2006 Jan;
78(1):85-90.
PMID: 16391896
In a phase II clinical trial, we sought to determine if combining celecoxib with 13-cis-retinoic acid (13-cRA, Accutane) was efficacious in the treatment of recurrent (progressive) glioblastoma multiforme (GBM). In...
8.
Levin V, Yung W, BRUNER J, Kyritsis A, LEEDS N, Gleason M, et al.
Int J Radiat Oncol Biol Phys
. 2002 May;
53(1):58-66.
PMID: 12007942
Purpose: To conduct a Phase II one-arm study to evaluate the long-term efficacy and safety of accelerated fractionated radiotherapy combined with i.v. carboplatin for patients with previously untreated anaplastic gliomas....
9.
Bondy M, Wang L, El-Zein R, de Andrade M, Selvan M, Bruner J, et al.
J Natl Cancer Inst
. 2001 Oct;
93(20):1553-7.
PMID: 11604478
Background: About 9% of human cancers are brain tumors, of which 90% are gliomas. gamma-Radiation has been identified as a risk factor for brain tumors. In a previous pilot study,...
10.
Levels of N7-(2-hydroxyethyl)guanine as a molecular dosimeter of drug delivery to human brain tumors
Bodell W, Giannini D, Hassenbusch S, Levin V
Neuro Oncol
. 2001 Oct;
3(4):241-5.
PMID: 11584893
The level of N7-(2-hydroxyethyl)guanine (N7-HOEtG), one of the DNA alkylation products formed by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) treatment, was measured in human brain tumor samples by high performance liquid chromatography with electrochemical...