Uwe Christians
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Explore the profile of Uwe Christians including associated specialties, affiliations and a list of published articles.
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Articles
229
Citations
2982
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Recent Articles
1.
Klawitter J, Easton M, Karpeisky A, Farrell K, Thamm D, Shokati T, et al.
Molecules
. 2025 Jan;
30(2).
PMID: 39860223
Background: The use of the bone-seeking properties of bisphosphonates (BPs) to target the delivery of therapeutic drugs is a promising approach for the treatment of bone metastases. Currently, the most...
2.
Sempio C, Campos-Palomino J, Klawitter J, Peters E, MacNair L, Haghdoost M, et al.
Pharmaceuticals (Basel)
. 2025 Jan;
17(12.
PMID: 39770444
Background: Tetrahydrocannabivarin (THCV) is a phytocannabinoid commonly found in cannabis with potential pharmacological properties; however, its post-acute pharmacokinetics (PK) in humans have not been studied yet. THCV has two isomers,...
3.
Moore B, Mueller N, Perng W, Sauder K, Hebert E, Hoyt A, et al.
Pediatr Obes
. 2024 Dec;
20(1):e13187.
PMID: 39681476
Background: Prenatal exposure to cannabis (or more specifically, delta 9-tetrahydrocannabinol [Δ9-THC]) has been consistently linked to low birthweight. Animal models further show that Δ9-THC is associated with rapid postnatal growth....
4.
Sempio C, Campos-Palomino J, Klawitter J, Zhao W, Huestis M, Christians U, et al.
Anal Bioanal Chem
. 2024 Dec;
417(4):761-769.
PMID: 39644381
Recently in the USA, kratom consumers increasingly report use of the plant for self-treatment of mood ailments, the lack of energy, chronic pain, and opioid withdrawal and dependence. Several alkaloids...
5.
Jakobs M, Trautmann L, Hadamitzky M, Bihorac J, Jacquet L, Christians U, et al.
Brain Behav
. 2024 Nov;
14(11):e70146.
PMID: 39552126
Background: Studies in experimental animals revealed that acute and chronic treatment with small-molecule immunosuppressive drugs lead to neurobehavioral alterations in rodents. Methods: Against this background, this study investigated behavioral alterations...
6.
Helmke S, McRae M, Christians U, Shokati T, Everson G
J Appl Lab Med
. 2024 Aug;
9(6):1028-1039.
PMID: 39150903
Background: Current methods for evaluating liver health rely on nonspecific blood tests, elastography surrogates for fibrosis, and invasive procedures, none of which directly measure liver function and physiology. Herein we...
7.
Younoszai N, Hollander C, Kinney G, Hamlington K, Klawitter J, Sempio C, et al.
Pediatr Pulmonol
. 2024 Jul;
59(12):3766-3769.
PMID: 39056509
No abstract available.
8.
Mayne G, DeWitt P, Wen J, Schniedewind B, Dabelea D, Christians U, et al.
J Clin Endocrinol Metab
. 2024 Jul;
110(2):523-533.
PMID: 38980936
Context: Adiponectin is a potent uterine tocolytic that decreases with gestational age, suggesting it could be a maternal metabolic quiescence factor. Maternal stress can influence preterm birth risk, and adiponectin...
9.
Odell E, Jabassini N, Schniedewind B, Pease-Raissi S, Frymoyer A, Christians U, et al.
Pediatr Res
. 2024 Jun;
96(4):933-941.
PMID: 38942888
Background: Preterm white matter injury (PWMI) is the most common cause of brain injury in premature neonates. PWMI involves a differentiation arrest of oligodendrocytes, the myelinating cells of the central...
10.
Ward A, Shokati T, Klawitter J, Klawitter J, Nguyen V, Kozell L, et al.
Metabolites
. 2024 Jun;
14(6).
PMID: 38921465
Cannabichromene (CBC) is a minor cannabinoid within the array of over 120 cannabinoids identified in the plant. While CBC does not comprise a significant portion of whole plant material, it...