Ute Laggner
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Explore the profile of Ute Laggner including associated specialties, affiliations and a list of published articles.
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10
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821
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Recent Articles
1.
Ng Kee Kwong F, Laggner U, McKinney O, Croud J, Rice A, Nicholson A
Histopathology
. 2018 Jan;
72(6):1024-1032.
PMID: 29323731
Aims: As immunomodulatory therapy is being integrated into treatment regimens for non-small-cell lung carcinoma, we aimed to prospectively collect data on the immunohistochemical profile of tumours assessed in our institution...
2.
Laggner U, Khiroya R, Wotherspoon A, Desai S, Nicholson A
Histopathology
. 2017 Sep;
72(4):704-706.
PMID: 28945277
No abstract available.
3.
Hundhausen C, Bertoni A, Mak R, Botti E, Di Meglio P, Clop A, et al.
J Invest Dermatol
. 2011 Nov;
132(3 Pt 1):635-41.
PMID: 22113476
Psoriasis is an inflammatory skin disorder that is inherited as a complex trait. Genetic studies have repeatedly highlighted HLA-C as the major determinant for psoriasis susceptibility, with the Cw*0602 allele...
4.
Laggner U, Di Meglio P, Perera G, Hundhausen C, Lacy K, Ali N, et al.
J Immunol
. 2011 Aug;
187(5):2783-93.
PMID: 21813772
γδ T cells mediate rapid tissue responses in murine skin and participate in cutaneous immune regulation including protection against cancer. The role of human γδ cells in cutaneous homeostasis and...
5.
Di Meglio P, Di Cesare A, Laggner U, Chu C, Napolitano L, Villanova F, et al.
PLoS One
. 2011 Mar;
6(2):e17160.
PMID: 21364948
IL-23 and Th17 cells are key players in tissue immunosurveillance and are implicated in human immune-mediated diseases. Genome-wide association studies have shown that the IL23R R381Q gene variant protects against...
6.
Tonel G, Conrad C, Laggner U, Di Meglio P, Grys K, McClanahan T, et al.
J Immunol
. 2010 Oct;
185(10):5688-91.
PMID: 20956338
Interleukin-23 is a key cytokine involved in the generation of Th17 effector cells. Clinical efficacy of an anti-p40 mAb blocking both IL-12 and IL-23 and disease association with single nucleotide...
7.
Conrad C, Boyman O, Tonel G, Tun-Kyi A, Laggner U, De Fougerolles A, et al.
Nat Med
. 2007 Jul;
13(7):836-42.
PMID: 17603494
Psoriasis is a common T cell-mediated autoimmune inflammatory disease. We show that blocking the interaction of alpha1beta1 integrin (VLA-1) with collagen prevented accumulation of epidermal T cells and immunopathology of...
8.
Haberler C, Laggner U, Slavc I, Czech T, Ambros I, Ambros P, et al.
Am J Surg Pathol
. 2006 Oct;
30(11):1462-8.
PMID: 17063089
Immunohistochemical lack of nuclear INI1 protein expression has been recently described as characteristic finding in atypical teratoid/rhabdoid tumors (AT/RTs), and has been suggested as useful marker to distinguish AT/RTs from...
9.
Gelpi E, Preusser M, Laggner U, Garzuly F, Holzmann H, Heinz F, et al.
J Neurovirol
. 2006 Sep;
12(4):322-7.
PMID: 16966222
In Central European tick-borne encephalitis (TBE) mechanisms of tissue destruction are poorly understood. To evaluate the contribution of immunological mechanisms to tissue injury, the authors immunohistochemically analyzed paraffin-embedded autoptic brain...
10.
Sadeghi K, Wessner B, Laggner U, Ploder M, Tamandl D, Friedl J, et al.
Eur J Immunol
. 2006 Jan;
36(2):361-70.
PMID: 16402404
Toll-like receptors (TLR) represent an ancient front-line defence system that enables the host organism to sense the presence of microbial components within minutes. As inducers of inflammation, TLR act as...