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Ute Frede

Explore the profile of Ute Frede including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 125
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Recent Articles
1.
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet A, Dumas M, et al.
Nat Commun . 2021 Jun; 12(1):3582. PMID: 34117224
In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanisms of this specificity remain unclear. Here, we demonstrate that the...
2.
Penter L, Maier B, Frede U, Hackner B, Carell T, Hagemeier C, et al.
Target Oncol . 2015 Jan; 10(4):523-33. PMID: 25559288
After extensive research on radiochemotherapy, 5-year survival rates of children with high risk neuroblastoma still do not exceed 50%, owing to adverse side-effects exemplified by doxorubicin-induced cardiomyopathy. A promising new...
3.
Pohlers M, Truss M, Frede U, Scholz A, Strehle M, Kuban R, et al.
Curr Biol . 2005 Jun; 15(11):1051-7. PMID: 15936277
E2F transcription factors play a pivotal role in the regulation of cellular proliferation and can be subdivided into activating and repressing family members [1]. Like other E2Fs, E2F6 binds to...
4.
Danckwardt S, Gehring N, Neu-Yilik G, Hundsdoerfer P, Pforsich M, Frede U, et al.
Blood . 2004 Apr; 104(2):428-35. PMID: 15059842
The functional analysis of the common prothrombin 20210 G>A(F2 20210(*)A) mutation has recently revealed gain of function of 3'end processing as a novel genetic mechanism predisposing to human disease. We...
5.
Danckwardt S, Neu-Yilik G, Thermann R, Frede U, Hentze M, Kulozik A
Blood . 2002 Feb; 99(5):1811-6. PMID: 11861299
Nonsense-mediated mRNA decay (NMD) represents a phylogenetically widely conserved splicing- and translation-dependent mechanism that eliminates transcripts with premature translation stop codons and suppresses the accumulation of C-terminally truncated peptides. Elimination...