Usha R Pendurthi
Overview
Explore the profile of Usha R Pendurthi including associated specialties, affiliations and a list of published articles.
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69
Citations
1316
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Recent Articles
1.
Das K, Keshava S, Kolesnick R, Pendurthi U, Rao L
J Thromb Haemost
. 2023 Nov;
22(2):441-454.
PMID: 37926194
Background: Factor VIIa induces the release of extracellular vesicles (EVs) from endothelial cells (EEVs). Factor VIIa-released EEVs are enriched with microRNA-10a (miR10a) and elicit miR10a-dependent cytoprotective responses. Objectives: To investigate...
2.
Das K, Keshava S, Mukherjee T, Wang J, Magisetty J, Kolesnick R, et al.
J Thromb Haemost
. 2023 Oct;
21(12):3414-3431.
PMID: 37875382
Background: Our recent studies showed that activated factor (F) VII (FVIIa) releases extracellular vesicles (EVs) from the endothelium. FVIIa-released EVs were found to be enriched with phosphatidylserine (PS) and contribute...
3.
Wang J, Keshava S, Das K, Kolesnick R, Jiang X, Pendurthi U, et al.
Arterioscler Thromb Vasc Biol
. 2022 Nov;
43(1):64-78.
PMID: 36412194
Background: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue factor) procoagulant activity. The current study was performed to investigate how alterations to sphingomyelin metabolic...
4.
Kondreddy V, Keshava S, Das K, Magisetty J, Rao L, Pendurthi U
Blood
. 2022 Jul;
140(13):1549-1564.
PMID: 35895897
Deep vein thrombosis (DVT) is the third most common cause of cardiovascular mortality. Several studies suggest that DVT occurs at the intersection of dysregulated inflammation and coagulation upon activation of...
5.
Das K, Pendurthi U, Manco-Johnson M, Martin E, Brophy D, Rao L
J Thromb Haemost
. 2022 May;
20(8):1928-1933.
PMID: 35608928
No abstract available.
6.
Magisetty J, Kondreddy V, Keshava S, Das K, Esmon C, Pendurthi U, et al.
Blood
. 2022 Feb;
139(18):2830-2841.
PMID: 35143636
Recurrent spontaneous or trauma-related bleeding into joints in hemophilia leads to hemophilic arthropathy (HA), a debilitating joint disease. Treatment of HA consists of preventing joint bleeding by clotting factor replacement,...
7.
Das K, Keshava S, Pendurthi U, Rao L
Blood
. 2021 Sep;
139(1):118-133.
PMID: 34469511
Coagulation protease, factor VIIa (FVIIa), binds to endothelial cell protein C receptor (EPCR) and induces anti-inflammatory and endothelial barrier protective responses via protease-activated receptor-1 (PAR1)-mediated, biased signaling. Our recent studies...
8.
Wang J, Pendurthi U, Yi G, Rao L
Blood
. 2021 Jun;
138(4):344-349.
PMID: 34075401
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with the hypercoagulable state. Tissue factor (TF) is the primary cellular initiator of coagulation. Most of the TF expressed on...
9.
Kondreddy V, Magisetty J, Keshava S, Rao L, Pendurthi U
Arterioscler Thromb Vasc Biol
. 2021 Apr;
41(6):1987-2005.
PMID: 33827252
[Figure: see text].
10.
Keshava S, Magisetty J, Tucker T, Kujur W, Mulik S, Esmon C, et al.
Am J Respir Cell Mol Biol
. 2021 Feb;
64(4):477-491.
PMID: 33600743
is the leading cause of hospital community-acquired pneumonia. Patients with pneumococcal pneumonia may develop complicated parapneumonic effusions or empyema that can lead to pleural organization and subsequent fibrosis. The pathogenesis...