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Ursula K Rohlwink

Explore the profile of Ursula K Rohlwink including associated specialties, affiliations and a list of published articles. Areas
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Citations 297
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Recent Articles
1.
Steyn C, Mishi R, Fillmore S, Verhoog M, More J, Rohlwink U, et al.
Nat Genet . 2024 Nov; 56(12):2718-2730. PMID: 39567748
The human brain undergoes protracted postnatal maturation, guided by dynamic changes in gene expression. Most studies exploring these processes have used bulk tissue analyses, which mask cell-type-specific gene expression dynamics....
2.
Wasserman S, Donovan J, Kestelyn E, Watson J, Aarnoutse R, Barnacle J, et al.
Lancet Infect Dis . 2024 Sep; 25(1):e47-e58. PMID: 39342951
Tuberculous meningitis causes death or disability in approximately 50% of affected individuals and kills approximately 78 200 adults every year. Antimicrobial treatment is based on regimens used for pulmonary tuberculosis,...
3.
Carstens G, Verbeek M, Rohlwink U, Figaji A, Te Brake L, van Laarhoven A
J Cereb Blood Flow Metab . 2024 Mar; 44(7):1063-1077. PMID: 38546534
Metabolomic analysis of cerebrospinal fluid (CSF) is used to improve diagnostics and pathophysiological understanding of neurological diseases. Alterations in CSF metabolite levels can partly be attributed to changes in brain...
4.
Steyn C, Mishi R, Fillmore S, Verhoog M, More J, Rohlwink U, et al.
bioRxiv . 2023 Oct; PMID: 37808657
The human brain undergoes protracted post-natal maturation, guided by dynamic changes in gene expression. Most studies exploring these processes have used bulk tissue analyses, which mask cell type-specific gene expression...
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Barichello T, Catalao C, Rohlwink U, van der Kuip M, Zaharie D, Solomons R, et al.
Front Neurol . 2023 Mar; 14:822575. PMID: 36864913
Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region, country, pathogen, and age group; being a life-threatening disease with a high case fatality rate and...
7.
Smith C, Rohlwink U, Mauff K, Thango N, Hina T, Salie S, et al.
Crit Care Med . 2023 Feb; 51(5):573-583. PMID: 36790173
Objectives: To examine cerebrovascular pressure reactivity index (PRx) in a large cohort of children with severe traumatic brain injury (sTBI) in association with physiologic variables and outcome. Design: Retrospective observational...
8.
Kim J, Erice C, Rohlwink U, Tucker E
Front Neurol . 2022 Mar; 13:805786. PMID: 35250814
Central nervous system (CNS) infections occur more commonly in young children than in adults and pose unique challenges in the developing brain. This review builds on the distinct vulnerabilities in...
9.
Singh G, Tucker E, Rohlwink U
Front Neurol . 2022 Feb; 12:805643. PMID: 35140675
Central nervous system (CNS) infections remain a major burden of pediatric disease associated with significant long-term morbidity due to injury to the developing brain. Children are susceptible to various etiologies...
10.
Loxton N, Rohlwink U, Tshavhungwe M, Dlamini L, Shey M, Enslin N, et al.
PLoS One . 2021 Mar; 16(3):e0246997. PMID: 33711020
Tuberculous meningitis (TBM) is the most fatal form of tuberculosis and frequently occurs in children. The inflammatory process initiates secondary brain injury processes that lead to death and disability. Much...