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Ursula Eilers

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Articles 6
Citations 401
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Recent Articles
1.
Bhandare P, Narain A, Hofstetter J, Rummel T, Wenzel J, Schulein-Volk C, et al.
Nucleic Acids Res . 2024 Dec; 53(4). PMID: 39698826
Transcripts produced by RNA polymerase II (RNAPII) are fundamental for cellular responses to environmental changes. It is therefore no surprise that there exist multiple avenues for the regulation of this...
2.
Krenz B, Gebhardt-Wolf A, Ade C, Gaballa A, Roehrig F, Vendelova E, et al.
Cancer Res . 2021 Jun; 81(16):4242-4256. PMID: 34145038
Deregulated expression of the MYC oncoprotein enables tumor cells to evade immune surveillance, but the mechanisms underlying this surveillance are poorly understood. We show here that endogenous MYC protects pancreatic...
3.
Endres T, Solvie D, Heidelberger J, Andrioletti V, Baluapuri A, Ade C, et al.
Mol Cell . 2021 Jan; 81(4):830-844.e13. PMID: 33453168
The MYC oncoprotein globally affects the function of RNA polymerase II (RNAPII). The ability of MYC to promote transcription elongation depends on its ubiquitylation. Here, we show that MYC and...
4.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, et al.
EMBO Mol Med . 2020 Mar; 12(4):e11101. PMID: 32128997
The transcription factor ∆Np63 is a master regulator of epithelial cell identity and essential for the survival of squamous cell carcinoma (SCC) of lung, head and neck, oesophagus, cervix and...
5.
Blattner S, Das S, Paprotka K, Eilers U, Krischke M, Kretschmer D, et al.
PLoS Pathog . 2016 Sep; 12(9):e1005857. PMID: 27632173
Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM). The pathogen...
6.
Otto T, Horn S, Brockmann M, Eilers U, Schuttrumpf L, Popov N, et al.
Cancer Cell . 2008 Dec; 15(1):67-78. PMID: 19111882
In human neuroblastoma, amplification of the MYCN gene predicts poor prognosis and resistance to therapy. In a shRNA screen of genes that are highly expressed in MYCN-amplified tumors, we have...