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Ursula Eilber

Explore the profile of Ursula Eilber including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 3070
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Recent Articles
1.
Wu L, Shi W, Long J, Guo X, Michailidou K, Beesley J, et al.
Nat Genet . 2018 Jun; 50(7):968-978. PMID: 29915430
The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknown....
2.
Horne H, Oh H, Sherman M, Palakal M, Hewitt S, Schmidt M, et al.
Sci Rep . 2018 Apr; 8(1):6574. PMID: 29700408
E-cadherin (CDH1) is a putative tumor suppressor gene implicated in breast carcinogenesis. Yet, whether risk factors or survival differ by E-cadherin tumor expression is unclear. We evaluated E-cadherin tumor immunohistochemistry...
3.
Block M, Vierkant R, Rambau P, Winham S, Wagner P, Traficante N, et al.
Mayo Clin Proc . 2018 Mar; 93(3):307-320. PMID: 29502561
Objective: To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial ovarian cancer, histologic subtypes, and overall survival....
4.
Obi N, Eulenburg C, Seibold P, Eilber U, Thone K, Behrens S, et al.
Breast . 2017 Dec; 38:75-80. PMID: 29248876
Background: Studies of cohorts of breast cancer (BC) patients diagnosed before 1990 showed radiotherapy (RT) to be associated with increased cardiovascular (CVD) and lung cancer mortality many years after diagnosis....
5.
Michailidou K, Lindstrom S, Dennis J, Beesley J, Hui S, Kar S, et al.
Nature . 2017 Oct; 551(7678):92-94. PMID: 29059683
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to breast cancer...
6.
Milne R, Kuchenbaecker K, Michailidou K, Beesley J, Kar S, Lindstrom S, et al.
Nat Genet . 2017 Oct; 49(12):1767-1778. PMID: 29058716
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative cases and 100,594...
7.
Barrdahl M, Rudolph A, Hopper J, Southey M, Broeks A, Fasching P, et al.
Int J Cancer . 2017 Jul; 141(9):1830-1840. PMID: 28670784
Investigating the most likely causal variants identified by fine-mapping analyses may improve the power to detect gene-environment interactions. We assessed the interplay between 70 single nucleotide polymorphisms identified by genetic...
8.
Phelan C, Kuchenbaecker K, Tyrer J, Kar S, Lawrenson K, Winham S, et al.
Nat Genet . 2017 Mar; 49(5):680-691. PMID: 28346442
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified...
9.
Southey M, Goldgar D, Winqvist R, Pylkas K, Couch F, Tischkowitz M, et al.
J Med Genet . 2016 Sep; 53(12):800-811. PMID: 27595995
Background: The rarity of mutations in PALB2, CHEK2 and ATM make it difficult to estimate precisely associated cancer risks. Population-based family studies have provided evidence that at least some of...
10.
Ong J, Cuellar-Partida G, Lu Y, Fasching P, Hein A, Burghaus S, et al.
Int J Epidemiol . 2016 Sep; 45(5):1619-1630. PMID: 27594614
Background: In vitro and observational epidemiological studies suggest that vitamin D may play a role in cancer prevention. However, the relationship between vitamin D and ovarian cancer is uncertain, with...