Ursula A Gompels
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Explore the profile of Ursula A Gompels including associated specialties, affiliations and a list of published articles.
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18
Citations
544
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Recent Articles
1.
Gompels U, Bravo F, Briggs S, Ameri S, Cardin R, Bernstein D
Viruses
. 2022 Nov;
14(11).
PMID: 36366414
Herpes simplex virus 1 and 2 infections cause high unmet disease burdens worldwide. Mainly HSV-2 causes persistent sexually transmitted disease, fatal neonatal disease and increased transmission of HIV/AIDS. Thus, there...
2.
Gatherer D, Depledge D, Hartley C, Szpara M, Vaz P, Benko M, et al.
J Gen Virol
. 2021 Oct;
102(10).
PMID: 34704922
Members of the family have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125-241 kbp contain 70-170 genes, of...
3.
Suarez N, Wilkie G, Hage E, Camiolo S, Holton M, Hughes J, et al.
J Infect Dis
. 2019 May;
220(5):781-791.
PMID: 31050742
The genomic characteristics of human cytomegalovirus (HCMV) strains sequenced directly from clinical pathology samples were investigated, focusing on variation, multiple-strain infection, recombination, and gene loss. A total of 207 datasets...
4.
Suarez N, Musonda K, Escriva E, Njenga M, Agbueze A, Camiolo S, et al.
J Infect Dis
. 2019 May;
220(5):792-801.
PMID: 31050737
Background: In developed countries, human cytomegalovirus (HCMV) is a major pathogen in congenitally infected and immunocompromised individuals, where multiple-strain infection appears linked to disease severity. The situation is less documented...
5.
Tweedy J, Escriva E, Topf M, Gompels U
Viruses
. 2018 Jan;
10(1).
PMID: 29301233
Tissue-culture adaptation of viruses can modulate infection. Laboratory passage and bacterial artificial chromosome (BAC)mid cloning of human cytomegalovirus, HCMV, resulted in genomic deletions and rearrangements altering genes encoding the virus...
6.
Tweedy J, Prusty B, Gompels U
Antiviral Res
. 2017 Sep;
146:201-204.
PMID: 28939478
New antivirals are required to prevent rising antimicrobial resistance from replication inhibitors. The aim of this study was to analyse the range of emerging mutations in herpesvirus by whole genome...
7.
Musonda K, Nyonda M, Filteau S, Kasonka L, Monze M, Gompels U
J Pediatric Infect Dis Soc
. 2016 Apr;
5(2):138-46.
PMID: 27103488
Background: Breastfeeding imparts beneficial immune protection and nutrition to infants for healthy growth, but it is also a route for human immunodeficiency virus (HIV) and human cytomegalovirus (HCMV) infection. In...
8.
Tweedy J, Spyrou M, Pearson M, Lassner D, Kuhl U, Gompels U
Viruses
. 2016 Jan;
8(1).
PMID: 26784220
Human herpesvirus-6A and B (HHV-6A, HHV-6B) have recently defined endogenous genomes, resulting from integration into the germline: chromosomally-integrated "CiHHV-6A/B". These affect approximately 1.0% of human populations, giving potential for virus...
9.
Ablashi D, Agut H, Alvarez-Lafuente R, Clark D, Dewhurst S, DiLuca D, et al.
Arch Virol
. 2013 Nov;
159(5):863-70.
PMID: 24193951
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on Taxonomy of Viruses (ICTV) classified HHV-6A and...
10.
Sanz-Ramos M, Manno D, Kapambwe M, Ndumba I, Musonda K, Bates M, et al.
Vaccine
. 2013 Mar;
31(16):2042-9.
PMID: 23474309
Background: Maternally HIV-exposed (mHIV-EU) infants have poor health even without HIV-1 infection. The responses to vaccination are less well defined. Immunity to oral Poliovirus vaccine (OPV) was studied in Zambian...