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» Authors » Upeksha P Chandrasiri

Upeksha P Chandrasiri

Explore the profile of Upeksha P Chandrasiri including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 172
Followers 0
Related Specialties
Tropical Medicine
Infectious Diseases
Science
Top 10 Co-Authors
Stephen J Rogerson
Per Ashorn
James G Beeson
Kenneth Maleta
Freya J I Fowkes
Kathryn G Dewey
Jack S Richards
Michael Grant
Shelley L Hedwards
Steve M Taylor
Published In
Malar J
J Infect Dis
Proc Natl Acad Sci U S A
Affiliations
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Recent Articles
1.
Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children
Barua P, Chandrasiri U, Beeson J, Dewey K, Maleta K, Ashorn P, et al.
Malar J . 2018 Feb; 17(1):74. PMID: 29415730
Background: There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of the study was to discover whether nutrient supplementation improved development...
2.
Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation
Chandrasiri U, Fowkes F, Beeson J, Richards J, Kamiza S, Maleta K, et al.
Malar J . 2016 Nov; 15(1):547. PMID: 27829430
Background: Malaria antibody responses measured at delivery have been associated with protection from maternal anaemia and low birth weight deliveries. Whether malarial antibodies present in the first half of pregnancy...
3.
The impact of lipid-based nutrient supplementation on anti-malarial antibodies in pregnant women in a randomized controlled trial
Chandrasiri U, Fowkes F, Richards J, Langer C, Fan Y, Taylor S, et al.
Malar J . 2015 May; 14:193. PMID: 25957793
Background: Malaria and undernutrition frequently coexist, especially in pregnant women and young children. Nutrient supplementation of these vulnerable groups might reduce their susceptibility to malaria by improving immunity. Methods: Antibody...
4.
Insight into the pathogenesis of fetal growth restriction in placental malaria: decreased placental glucose transporter isoform 1 expression
Chandrasiri U, Chua C, Umbers A, Chaluluka E, Glazier J, Rogerson S, et al.
J Infect Dis . 2013 Dec; 209(10):1663-7. PMID: 24325968
Placental malaria, especially when complicated with intervillositis, can cause fetal growth restriction. Transplacental glucose transport by glucose transporter isoform 1 (GLUT-1) on the syncytiotrophoblast microvillous and basal plasma membranes regulates...
5.
Low antibody levels to pregnancy-specific malaria antigens and heightened cytokine responses associated with severe malaria in pregnancy
Chandrasiri U, Randall L, Saad A, Bashir A, Rogerson S, Adam I
J Infect Dis . 2013 Nov; 209(9):1408-17. PMID: 24277742
Background:  Pregnant women living in unstable malaria transmission settings may develop severe malaria (SM). The pathogenesis of SM in pregnancy is poorly understood. Methods:  To determine whether SM in pregnancy...
6.
Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated
McPherson S, Hussain S, Balanathan P, Hedwards S, Niranjan B, Grant M, et al.
Proc Natl Acad Sci U S A . 2010 Feb; 107(7):3123-8. PMID: 20133657
Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are androgen-dependent diseases commonly treated by inhibiting androgen action. However, androgen ablation or castration fail to target androgen-independent cells implicated in disease...