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Unsu Jung

Explore the profile of Unsu Jung including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 188
Followers 0
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Recent Articles
1.
Mariotti J, Foley J, Jung U, Borenstein T, Kantardzic N, Han S, et al.
J Immunol . 2007 Dec; 180(1):89-105. PMID: 18097008
Because ex vivo rapamycin generates murine Th2 cells that prevent Graft-versus-host disease more potently than control Th2 cells, we hypothesized that rapamycin would generate Th2/Tc2 cells (Th2/Tc2.R cells) that abrogate...
2.
Jung U, Foley J, Erdmann A, Toda Y, Borenstein T, Mariotti J, et al.
Biol Blood Marrow Transplant . 2006 Aug; 12(9):905-18. PMID: 16920556
Rapamycin prevention of murine graft-versus-host disease (GVHD) is associated with a shift toward Th2- and Tc2-type cytokines. Recently, we found that use of rapamycin during ex vivo donor Th2 cell...
3.
Foley J, Jung U, Miera A, Borenstein T, Mariotti J, Eckhaus M, et al.
J Immunol . 2005 Oct; 175(9):5732-43. PMID: 16237064
Rapamycin (sirolimus) inhibits graft-vs-host disease (GVHD) and polarizes T cells toward Th2 cytokine secretion after allogeneic bone marrow transplantation (BMT). Therefore, we reasoned that ex vivo rapamycin might enhance the...
4.
Erdmann A, Gao Z, Jung U, Foley J, Borenstein T, Jacobson K, et al.
Blood . 2005 Mar; 105(12):4707-14. PMID: 15746085
To evaluate the direct effect of adenosine on cytokine-polarized effector T cells, murine type 1 helper T cells (Th1) and type 1 cytotoxic T lymphocytes (Tc1) and Th2/Tc2 cells were...
5.
Erdmann A, Jung U, Foley J, Toda Y, Fowler D
Biol Blood Marrow Transplant . 2004 Aug; 10(9):604-13. PMID: 15319772
CD3/CD28 co-stimulation activates T-cell cytokine and cytolytic effector function and therefore represents an approach to modulate donor T cells before allogeneic bone marrow transplantation (BMT). We hypothesized that co-stimulation of...
6.
Jung U, Foley J, Erdmann A, Eckhaus M, Fowler D
Blood . 2003 Jul; 102(9):3439-46. PMID: 12855580
Adoptive T-cell therapy using CD3/CD28 co-stimulation likely requires in vivo generation of antigen specificity. Because CD28 promotes TH1/TC1 (T1) or TH2/TC2 (T2) differentiation, costimulation may generate donor T1 or T2...