Una Fitzgerald
Overview
Explore the profile of Una Fitzgerald including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
955
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Recent Articles
1.
Martin-Saldana S, Al-Waeel M, Bagnoli E, Chevalier M, Bu Y, Lally C, et al.
Mater Horiz
. 2025 Mar;
PMID: 40067190
Multiple sclerosis (MS) is the main neurodegenerative disorder among young adults. Cortical involvement in MS has emerged as an important determinant of disease progression. Although inflammation is recognized as a...
2.
Ahmed M, Kakunuri T, Peris L, Meffre D, Yilmaz E, Grewing L, et al.
Brain Commun
. 2025 Feb;
7(1):fcae473.
PMID: 39926615
Lesions in the CNS are frequently associated to a detrimental inflammatory reaction. In autoimmune neurodegenerative diseases, a proliferation-inducing ligand (APRIL) produced by CNS-infiltrating inflammatory cells binds to chondroitin sulphate proteoglycans...
3.
Di Stefano J, Di Marco F, Cicalini I, Fitzgerald U, Pieragostino D, Verhoye M, et al.
Neural Regen Res
. 2024 Dec;
PMID: 39665813
Brain organoids encompass a large collection of in vitro stem cell-derived 3D culture systems that aim to recapitulate multiple aspects of in vivo brain development and function. First, this review...
4.
Habibah T, Matonohova J, Kulhanek J, Fitzgerald U, Ingr M, Pravda M, et al.
Carbohydr Polym
. 2024 Aug;
343:122455.
PMID: 39174092
Polysaccharides like hyaluronan (HA) and chondroitin sulfate (CS) are native of the brain's extracellular matrix crucial for myelination and brain maturation. Despite extensive research on HA and CS as drug...
5.
Di Stefano J, Garcia-Pupo L, Di Marco F, Motaln H, Govaerts J, Van Breedam E, et al.
Brain Behav Immun
. 2024 Jul;
121:1-12.
PMID: 39002812
induced-pluripotent stem cell (iPSC)-derived neurospheroid (NSPH) models are an emerging in vitro toolkit to study the influence of inflammatory triggers on neurodegeneration and repair in a 3D neural environment. In...
6.
Bagnoli E, Trotier A, McMahon J, Quinlan L, Biggs M, Pandit A, et al.
FASEB J
. 2023 Nov;
37(12):e23272.
PMID: 37997495
Parkinson's disease (PD) is a progressive, neurodegenerative disorder with an increasing incidence, unknown etiology, and is currently incurable. Advances in understanding the pathological mechanisms at a molecular level have been...
7.
Trotier A, Bagnoli E, Walski T, Evers J, Pugliese E, Lowery M, et al.
Adv Sci (Weinh)
. 2023 Jul;
10(27):e2301352.
PMID: 37518828
The development of bioelectronic neural implant technologies has advanced significantly over the past 5 years, particularly in brain-machine interfaces and electronic medicine. However, neuroelectrode-based therapies require invasive neurosurgery and can...
8.
Shologu N, Gurdal M, Szegezdi E, Fitzgerald U, Zeugolis D
Biomaterials
. 2022 Jun;
287:121642.
PMID: 35724540
Although cell-derived matrices are at the forefront of scientific research and technological innovation for the development of in vitro tumour models, their two-dimensional structure and low extracellular matrix composition restrict...
9.
Bagnoli E, Diviney T, Fitzgerald U
Eur J Neurosci
. 2020 May;
53(9):2960-2972.
PMID: 32353182
The monoamine oxidase metabolite of dopamine, 3,4-dihydroxyphenylacetaldehyde (DOPAL), is hypothesized to induce neurodegeneration in Parkinson's disease (PD). However, DOPAL's effect on astrocyte function is less well known. Furthermore, the conflicting...
10.
Naughton M, McMahon J, Healy S, Fitzgerald U
J Comp Neurol
. 2019 May;
527(17):2910-2924.
PMID: 31132146
The unfolded protein response (UPR) has been reported during normal development of cortical neurons and cerebellar white matter and may also contribute to the pathogenesis of neurological conditions, such as...