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Umut A Gurkan

Explore the profile of Umut A Gurkan including associated specialties, affiliations and a list of published articles. Areas
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Articles 79
Citations 1248
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Recent Articles
1.
Goreke U, Gonzales A, Shipley B, Tincher M, Sharma O, Wulftange W, et al.
Nat Commun . 2024 Aug; 15(1):7058. PMID: 39152149
Imaging and characterizing the dynamics of cellular adhesion in blood samples is of fundamental importance in understanding biological function. In vitro microscopy methods are widely used for this task but...
2.
Oshabaheebwa S, Delianides C, Patwardhan A, Evans E, Sekyonda Z, Bode A, et al.
Biosens Bioelectron . 2024 May; 258():116352. PMID: 38718635
The production of HbS - an abnormal hemoglobin (Hb) - in sickle cell disease (SCD) results in poorly deformable red blood cells (RBCs) that are prone to microcapillary occlusion, causing...
3.
Diem S, Bayon B, Mahmoud H, Garcia-Cazarin M, Martin M, Rittschof C, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(18):e2404579121. PMID: 38657043
No abstract available.
4.
Sekyonda Z, An R, Goreke U, Man Y, Monchamp K, Bode A, et al.
Analyst . 2024 Mar; 149(9):2561-2572. PMID: 38501195
Oxygen (O) binds to hemoglobin (Hb) in the lungs and is then released (dissociated) in the tissues. The Bohr effect is a physiological mechanism that governs the affinity of Hb...
5.
Gurkan U, Wood D, Carranza D, Herbertson L, Diamond S, Du E, et al.
Lab Chip . 2024 Mar; 24(7):1867-1874. PMID: 38487919
Microfluidic lab-on-a-chip technologies enable the analysis and manipulation of small fluid volumes and particles at small scales and the control of fluid flow and transport processes at the microscale, leading...
6.
Ghosh S, Man Y, Fraiwan A, Waters C, McKenzie C, Lu C, et al.
Cell Rep Med . 2024 Mar; 5(3):101447. PMID: 38442713
There is an unmet clinical need for a non-invasive and cost-effective test for oral squamous cell carcinoma (OSCC) that informs clinicians when a biopsy is warranted. Human beta-defensin 3 (hBD-3),...
7.
Isiksacan Z, DAlessandro A, McKenna D, Tessier S, Kucukal E, Gokaltun A, et al.
Proc Natl Acad Sci U S A . 2024 Mar; 121(11):e2320521121. PMID: 38437566
No abstract available.
8.
An R, Avanaki A, Thota P, Nemade S, Mehta A, Gurkan U
Biosensors (Basel) . 2024 Feb; 14(2). PMID: 38392002
Hemoglobin (Hb) disorders are among the most common monogenic diseases affecting nearly 7% of the world population. Among various Hb disorders, approximately 1.5% of the world population carries -thalassemia (-Thal),...
9.
Wegierak D, Cooley M, Perera R, Wulftange W, Gurkan U, Kolios M, et al.
IEEE Trans Med Imaging . 2024 Feb; 43(6):2370-2380. PMID: 38329864
Nanobubbles (NBs; ~100-500 nm diameter) are preclinical ultrasound (US) contrast agents that expand applications of contrast enhanced US (CEUS). Due to their sub-micron size, high particle density, and deformable shell,...
10.
Goreke U, Gonzales A, Shipley B, Tincher M, Sharma O, Wulftange W, et al.
bioRxiv . 2023 Oct; PMID: 37873474
Imaging and characterizing the dynamics of cellular adhesion in blood samples is of fundamental importance in understanding biological function. microscopy methods are widely used for this task, but typically require...