Umit A Kayisli
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Explore the profile of Umit A Kayisli including associated specialties, affiliations and a list of published articles.
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73
Citations
1117
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Recent Articles
11.
Guzeloglu-Kayisli O, Semerci N, Guo X, Larsen K, Ozmen A, Arlier S, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(11).
PMID: 33836562
Depression and posttraumatic stress disorder increase the risk of idiopathic preterm birth (iPTB); however, the exact molecular mechanism is unknown. Depression and stress-related disorders are linked to increased FK506-binding protein...
12.
Sprague R, Kim J, Kirimlioglu E, Guo X, Gunay N, Guzeloglu-Kayisli O, et al.
J Clin Endocrinol Metab
. 2020 Nov;
106(2):337-350.
PMID: 33247592
Context: Enhanced levels of catecholestradiols, 2-hydroxyestradiol (2-OHE2) or 4-hydroxyestradiol (4-OHE2), are reported in endometriosis. During gestation, catecholestradiol activation of adrenergic receptors (AR) elevates estrogen receptor (ER)-independent proliferation of uterine arterial...
13.
Mong E, Yang Y, Akat K, Canfield J, VanWye J, Lockhart J, et al.
Sci Rep
. 2020 Feb;
10(1):3029.
PMID: 32080251
During implantation, cytotrophoblasts undergo epithelial-to-mesenchymal transition (EMT) as they differentiate into invasive extravillous trophoblasts (EVTs). The primate-specific microRNA cluster on chromosome 19 (C19MC) is exclusively expressed in the placenta, embryonic...
14.
Sinkey R, Guzeloglu-Kayisli O, Arlier S, Guo X, Semerci N, Moore R, et al.
Am J Pathol
. 2020 Jan;
190(2):388-399.
PMID: 31955792
Preterm premature rupture of membranes (PPROM) and thrombin generation by decidual cell-expressed tissue factor often accompany abruptions. Underlying mechanisms remain unclear. We hypothesized that thrombin-induced colony-stimulating factor-2 (CSF-2) in decidual...
15.
Beck S, Buhimschi I, Summerfield T, Ackerman W, Guzeloglu-Kayisli O, Kayisli U, et al.
Am J Reprod Immunol
. 2019 Feb;
81(4):e13100.
PMID: 30758898
Problem: Among mechanisms triggering onset of parturition, it has been recently postulated that Toll-Like Receptor (TLR)9 engagement by cell-free DNA (cfDNA) triggers inflammation, myometrial contractions, and labor in absence of...
16.
Canfield J, Arlier S, Mong E, Lockhart J, VanWye J, Guzeloglu-Kayisli O, et al.
FASEB J
. 2018 Oct;
33(2):2759-2769.
PMID: 30307771
Preeclampsia (PE) is a common cause of maternal morbidity, characterized by impaired trophoblast invasion and spiral artery transformation resulting in progressive uteroplacental hypoxia. Given the primary role of LIN28A and...
17.
Arlier S, Murk W, Guzeloglu-Kayisli O, Semerci N, Larsen K, Tabak M, et al.
Am J Reprod Immunol
. 2017 Sep;
78(6).
PMID: 28921734
Problem: The role of extracellular signal-regulated kinase (ERK)1/2-mediated angiogenesis during endometriotic nidation is unknown. We posit that ERK1/2-induced angioblast differentiation and proliferation promotes ectopic endometrial angiogenesis. Methods Of Study: Human...
18.
Cakmak H, Seval-Celik Y, Arlier S, Guzeloglu-Kayisli O, Schatz F, Arici A, et al.
Reprod Sci
. 2017 Aug;
25(4):587-597.
PMID: 28845752
Background: Local pro-inflammatory environment and enhanced cell survival contribute to the endometriosis development. A serine/threonine kinase p38 mitogen-activated protein kinase (MAPK) mediates intracellular signaling of cytokine production, cell proliferation, and...
19.
Shapiro J, Guzeloglu-Kayisli O, Kayisli U, Semerci N, Huang S, Arlier S, et al.
Contraception
. 2017 Apr;
95(6):592-601.
PMID: 28433626
Objective: Progestin-only contraceptives induce abnormal uterine bleeding, accompanied by prothrombin leakage from dilated endometrial microvessels and increased thrombin generation by human endometrial stromal cell (HESC)-expressed tissue factor. Initial studies of...
20.
Yen C, Kim S, Liao S, Atabekoglu C, Uckac S, Arici A, et al.
Fertil Steril
. 2017 Jan;
107(3):803-812.
PMID: 28069177
Objective: To study the impact of integrin-linked kinase (ILK) in endometrial stromal cells (ESCs) during decidualization. Design: Laboratory study with the use of human endometrium. Setting: University hospital. Patient(s): Fertile...