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Umesh S Deshmukh

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Articles 46
Citations 808
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Recent Articles
1.
Papinska J, Durslewicz J, Bagavant H, Deshmukh U
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892170
Elevated oxidative stress can play a pivotal role in autoimmune diseases by exacerbating inflammatory responses and tissue damage. In Sjögren's disease (SjD), the contribution of oxidative stress in the disease...
2.
Bagavant H, Durslewicz J, Pyclik M, Makuch M, Papinska J, Deshmukh U
Geroscience . 2024 Apr; 46(6):6085-6099. PMID: 38656650
Sjögren's disease (SjD), characterized by circulating autoantibodies and exocrine gland inflammation, is typically diagnosed in women over 50 years of age. However, the contribution of age to SjD pathogenesis is...
3.
Bagavant H, Durslewicz J, Pyclik M, Makuch M, Papinska J, Deshmukh U
bioRxiv . 2024 Feb; PMID: 38405963
Sjögren's disease (SjD), characterized by circulating autoantibodies and exocrine gland inflammation, is typically diagnosed in women over 50 years of age. However, the contribution of age to SjD pathogenesis is...
4.
Garman L, Pezant N, Dawkins B, Rasmussen A, Levin A, Rybicki B, et al.
Am J Respir Crit Care Med . 2023 Jun; 209(1):106-109. PMID: 37348127
No abstract available.
5.
Pyclik M, Durslewicz J, Papinska J, Deshmukh U, Bagavant H
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36835537
Activation of the Stimulator of Interferon Genes (STING) protein has paradoxical outcomes in skin disease. STING activation exacerbates psoriatic skin disease and delays wound healing in diabetic mice, yet it...
6.
Bagavant H, Araszkiewicz A, Rasmussen A, Pezant N, Montgomery C, Scofield R, et al.
Clin Immunol . 2023 Jan; 247:109243. PMID: 36702181
Vimentin is a ubiquitously present Type III intermediate filament protein, often targeted by autoimmune responses in multiple rheumatic disorders. Although previous studies have reported anti-vimentin antibodies in Sjögren's disease (SjD)...
7.
Bagavant H, Trzeciak M, Biswas I, Papinska J, Cizio K, Deshmukh U
J Oral Pathol Med . 2022 Jun; 51(7):674-677. PMID: 35766433
Background: Oral and ocular dryness due to reduced saliva and tear production, exocrine gland inflammation, and autoantibodies to multiple cellular proteins are the cardinal features of Sjögren's Disease. Among the...
8.
Bagavant H, Cizio K, Araszkiewicz A, Papinska J, Garman L, Li C, et al.
J Transl Autoimmun . 2022 Apr; 5():100153. PMID: 35434591
A characteristic feature of sarcoidosis is a dysregulated immune response to persistent stimuli, often leading to the formation of non-necrotizing granulomas in various organs. Although genetic susceptibility is an essential...
9.
Bagavant H, Araszkiewicz A, Ingram J, Cizio K, Merrill J, Arriens C, et al.
Front Immunol . 2021 Jun; 12():635072. PMID: 34122404
Interactions between gut microbes and the immune system influence autoimmune disorders like systemic lupus erythematosus (SLE). Recently, , a gram-positive commensal gut bacterium, was implicated as a candidate pathobiont in...
10.
Garman L, Pelikan R, Rasmussen A, Lareau C, Savoy K, Deshmukh U, et al.
Front Immunol . 2020 Dec; 11:567342. PMID: 33363531
Sarcoidosis is a systemic inflammatory disease characterized by infiltration of immune cells into granulomas. Previous gene expression studies using heterogeneous cell mixtures lack insight into cell-type-specific immune dysregulation. We performed...