Umesh B Mahajan
Overview
Explore the profile of Umesh B Mahajan including associated specialties, affiliations and a list of published articles.
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31
Citations
527
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Recent Articles
1.
Pawar G, Agrawal Y, Nakhate K, Patil C, Sharma C, Ojha S, et al.
Am J Transl Res
. 2022 Nov;
14(10):7098-7108.
PMID: 36398212
Objectives: In the era of globalization, a sedentary lifestyle is highly linked with obesity and neurobehavioral complications such as depression. While depression is associated with dopamine dysfunction in the ventral...
2.
Masule M, Rathod S, Agrawal Y, Patil C, Nakhate K, Ojha S, et al.
Curr Res Pharmacol Drug Discov
. 2022 Jul;
3:100113.
PMID: 35782191
Ghrelin is a peptide released by the endocrine cells of the stomach and the neurons in the arcuate nucleus of the hypothalamus. It modulates both peripheral and central functions. Although...
3.
Prajapati C, Agrawal Y, Agnihotri V, Mahajan U, Patil K, Patil D, et al.
Int J Biol Macromol
. 2022 Jun;
214:391-401.
PMID: 35714868
Thymoquinone (TQ), the most prominent constituent of Nigella sativa seeds, essential oil, is reported to possess an organ protective effect via Nrf2 expression and activation of Phase-II antioxidant enzymes. Haemorrhagic...
4.
Pawar H, Mahajan U, Nakhate K, Agrawal Y, Patil C, Meeran M, et al.
Life (Basel)
. 2022 May;
12(5).
PMID: 35629293
Molecular docking revealed curcumin as a potent CB2 cannabinoid receptor (CB2R) agonist. Since CB2R is involved in cardioprotective functions, we explored its role in ameliorative actions of curcumin against myocardial...
5.
Agrawal Y, Mahajan U, Agnihotri V, Nilange M, Mahajan H, Sharma C, et al.
Molecules
. 2021 Apr;
26(5).
PMID: 33803259
Ezetimibe (EZE) possesses low aqueous solubility and poor bioavailability and in addition, its extensive hepatic metabolism supports the notion of developing a novel carrier system for EZE. Ezetimibe was encapsulated...
6.
Patil A, Mahajan U, Agrawal Y, Patil K, Patil C, Ojha S, et al.
Biomed Pharmacother
. 2020 Oct;
132:110889.
PMID: 33113429
The endocannabinoid system (ECS) is natural physiological system in the humans. The presence of the ECS system involves different roles in body. The endocannabinoid system involves regulation of most of...
7.
Birari L, Wagh S, Patil K, Mahajan U, Unger B, Belemkar S, et al.
Cancer Chemother Pharmacol
. 2020 Aug;
86(3):419-426.
PMID: 32812061
Purpose: Aloin, an anthraquinone present in the aloe species, possesses antiangiogenic, chemopreventive and antioxidant properties. It exerts cytotoxicity against breast cancer and ovarian cancer cell lines. These properties of aloin...
8.
Agrawal Y, Mahajan U, Mahajan H, Ojha S
Int J Nanomedicine
. 2020 Aug;
15:4763-4778.
PMID: 32753865
Introduction: Methotrexate exhibits poor cutaneous bioavailability and systemic side effects on topical administration, so there is an unmet need for a novel carrier and its optimized therapy. Methotrexate-loaded nanostructured lipid...
9.
Birari L, Mahajan U, Patil K, Patil D, Bagul N, Belemkar S, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2020 Feb;
393(8):1365-1372.
PMID: 32025748
Aloin exerts concentration-dependent pro-oxidant and antioxidant effects when tested in vitro. Such duality of effects has not been investigated through in vivo studies on aloin. We evaluated the effects of...
10.
Patil K, Mahajan U, Unger B, Goyal S, Belemkar S, Surana S, et al.
Int J Mol Sci
. 2019 Sep;
20(18).
PMID: 31491986
Inflammation is one of the common events in the majority of acute as well as chronic debilitating diseases and represent a chief cause of morbidity in today's era of modern...