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Umberto Galderisi

Explore the profile of Umberto Galderisi including associated specialties, affiliations and a list of published articles. Areas
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Articles 135
Citations 3778
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Recent Articles
1.
Samiminemati A, Shahzaib M, Moriello C, Alessio N, Aprile D, Squillaro T, et al.
Methods Mol Biol . 2024 Dec; PMID: 39714585
Mesenchymal stromal cells (MSCs) are a heterogeneous population of non-hematopoietic adult stem cells derived from the embryonic mesoderm. They possess self-renewal and multipotent differentiation capabilities, allowing them to give rise...
2.
Samiminemati A, Shahzaib M, Moriello C, Alessio N, Aprile D, Squillaro T, et al.
Methods Mol Biol . 2024 Dec; PMID: 39702863
Cellular senescence is a multifaceted process marked by irreversible cell cycle arrest in response to stressors such as DNA damage, oxidative stress, and telomere shortening, leading to significant cellular and...
3.
Siraj Y, Aprile D, Alessio N, Peluso G, Di Bernardo G, Galderisi U
Cell Commun Signal . 2024 Nov; 22(1):540. PMID: 39533382
Senescent cells exert their effects through the release of various factors, collectively referred to as the senescence-associated secretory phenotype (SASP). The SASP can induce senescence in healthy cells (secondary senescence),...
4.
Mosca N, Alessio N, Di Paola A, Marrapodi M, Galderisi U, Russo A, et al.
J Biomed Sci . 2024 Jun; 31(1):59. PMID: 38835012
Osteosarcoma (OS) is the most prevalent and fatal type of bone tumor. It is characterized by great heterogeneity of genomic aberrations, mutated genes, and cell types contribution, making therapy and...
5.
Aprile D, Patrone D, Peluso G, Galderisi U
Stem Cell Res Ther . 2024 May; 15(1):139. PMID: 38735988
The concept of "stemness" incorporates the molecular mechanisms that regulate the unlimited self-regenerative potential typical of undifferentiated primitive cells. These cells possess the unique ability to navigate the cell cycle,...
6.
Alessio N, Ambrosino A, Boggi A, Aprile D, Pinto I, Galano G, et al.
Aging (Albany NY) . 2024 May; 16(9):7511-7522. PMID: 38700499
The battle against the COVID-19 pandemic has spurred a heightened state of vigilance in global healthcare, leading to the proliferation of diverse sanitization methods. Among these approaches, germicidal lamps utilizing...
7.
Siniscalco D, Galderisi U, Peluso G, Finicelli M
Int J Mol Sci . 2024 Mar; 25(6). PMID: 38542114
Circulating microRNAs (c-miRNAs) are non-coding RNAs found in different bodily fluids and are highly investigated for their prognostic potential and biological role in cancer. In this narrative review, we provide...
8.
Alessio N, Aprile D, Peluso G, Mazzone V, Patrone D, Di Bernardo G, et al.
Cell Commun Signal . 2024 Feb; 22(1):122. PMID: 38351010
Cells that are exposed to harmful genetic damage, either from internal or external sources, may undergo senescence if they are unable to repair their DNA. Senescence, characterized by a state...
9.
Oguma Y, Alessio N, Aprile D, Dezawa M, Peluso G, Di Bernardo G, et al.
Cell Commun Signal . 2023 Sep; 21(1):262. PMID: 37770897
DNA damage resulting from genotoxic injury can initiate cellular senescence, a state characterized by alterations in cellular metabolism, lysosomal activity, and the secretion of factors collectively known as the senescence-associated...
10.
Valentino A, Leuci S, Galderisi U, Spagnuolo G, Mignogna M, Peluso G, et al.
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37511259
The mucosal-dominant variant of pemphigus vulgaris (MPV) is an autoimmune disease characterized by oral mucosal blistering and circulating pathogenic IgG antibodies against desmoglein 3 (Dsg3), resulting in life-threatening bullae and...