Uladzislau Rudakou
Overview
Explore the profile of Uladzislau Rudakou including associated specialties, affiliations and a list of published articles.
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21
Citations
279
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Recent Articles
1.
Sosero Y, Bandres-Ciga S, Ferwerda B, Tocino M, Belloso D, Gomez-Garre P, et al.
Mov Disord
. 2024 Aug;
39(10):1773-1783.
PMID: 39132902
Background: Levodopa-induced dyskinesia (LID) is a common adverse effect of levodopa, one of the main therapeutics used to treat the motor symptoms of Parkinson's disease (PD). Previous evidence suggests a...
2.
Sosero Y, Bandres-Ciga S, Ferwerda B, Tocino M, Belloso D, Gomez-Garre P, et al.
medRxiv
. 2023 Oct;
PMID: 37790572
Background: Levodopa-induced dyskinesia (LID) is a common adverse effect of levodopa, one of the main therapeutics used to treat the motor symptoms of Parkinson's disease (PD). Previous evidence suggests a...
3.
Somerville E, Krohn L, Yu E, Rudakou U, Senkevich K, Ruskey J, et al.
Neurobiol Aging
. 2023 Apr;
127:94-98.
PMID: 37032242
NPC1 encodes a lysosomal protein involved in cholesterol transport. Biallelic mutations in this gene may lead to Niemann-Pick disease type C (NPC), a lysosomal storage disorder. The role of NPC1...
4.
Senkevich K, Rudakou U, Gan-Or Z
Handb Clin Neurol
. 2023 Feb;
193:155-170.
PMID: 36803808
Genetic variants in GBA, encoding the lysosomal enzyme glucocerebrosidase (GCase), are common risk factors for Parkinson's disease (PD). Genotype-phenotype studies have demonstrated that different types of GBA variants have differential...
5.
Krohn L, Heilbron K, Blauwendraat C, Reynolds R, Yu E, Senkevich K, et al.
Nat Commun
. 2022 Dec;
13(1):7496.
PMID: 36470867
Rapid-eye movement (REM) sleep behavior disorder (RBD), enactment of dreams during REM sleep, is an early clinical symptom of alpha-synucleinopathies and defines a more severe subtype. The genetic background of...
6.
Senkevich K, Zorca C, Dworkind A, Rudakou U, Somerville E, Yu E, et al.
Brain
. 2022 Nov;
146(5):1859-1872.
PMID: 36370000
The association between glucocerebrosidase, encoded by GBA, and Parkinson's disease (PD) highlights the role of the lysosome in PD pathogenesis. Genome-wide association studies in PD have revealed multiple associated loci,...
7.
Sosero Y, Yu E, Estiar M, Krohn L, Mufti K, Rudakou U, et al.
J Parkinsons Dis
. 2021 Oct;
12(1):333-340.
PMID: 34690151
Background: PSAP encodes saposin C, the co-activator of glucocerebrosidase, encoded by GBA. GBA mutations are associated with idiopathic/isolated REM sleep behavior disorder (iRBD), a prodromal stage of synucleinopathy. Objective: To...
8.
Senkevich K, Rudakou U, Gan-Or Z
Neuropharmacology
. 2021 Oct;
202:108822.
PMID: 34626666
Parkinson's disease (PD) is defined as a complex disorder with multifactorial pathogenesis, yet a more accurate definition could be that PD is not a single entity, but rather a mixture...
9.
Sosero Y, Yu E, Krohn L, Rudakou U, Mufti K, Ruskey J, et al.
Neurobiol Aging
. 2021 Mar;
103:142.e1-142.e5.
PMID: 33781610
The LRRK2 p.G2019S Parkinson's disease (PD) variant is associated with elevated glucocerebrosidase (GCase) activity in peripheral blood. We aimed to evaluate the association of other LRRK2 variants with PD and...
10.
Mufti K, Yu E, Rudakou U, Krohn L, Ruskey J, Asayesh F, et al.
Neurology
. 2021 Jan;
96(10):e1402-e1412.
PMID: 33397775
Objective: To examine the role of genes identified through genome-wide association studies (GWASs) of Parkinson disease (PD) in the risk of isolated REM sleep behavior disorder (iRBD). Methods: We fully...