U A Simanowski
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Explore the profile of U A Simanowski including associated specialties, affiliations and a list of published articles.
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35
Citations
307
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Recent Articles
1.
Vincon P, Wunderer J, Simanowski U, Koll M, Preedy V, Peters T, et al.
Alcohol Clin Exp Res
. 2003 Jan;
27(1):100-6.
PMID: 12544013
Background: Chronic alcohol consumption results in colorectal mucosal hyperregeneration, a condition associated with an increased risk for colorectal cancer. Possible mechanisms may involve the effects of acetaldehyde and/or free radicals...
2.
Koll M, Ahmed S, Mantle D, Donohue T, Palmer T, Simanowski U, et al.
Metabolism
. 2002 Jan;
51(1):97-104.
PMID: 11782879
Alcohol can be considered as a nutritional toxin when ingested in excess amounts and leads to skeletal muscle myopathy. We hypothesized that altered protease activities contribute to this phenomenon, and...
3.
Stickel F, Urbaschek R, Schuppan D, Poeschl G, Oesterling C, Conradt C, et al.
Dig Dis Sci
. 2001 Sep;
46(9):2025-32.
PMID: 11575459
Hepatic fibrosis in alcoholic liver disease often heralds progression to cirrhosis and, therefore, noninvasive parameters are required for early diagnosis and follow-up. Collagens VI and XIV, procollagen-III-N-propeptide, hyaluronic acid, and...
4.
Simanowski U, Homann N, Knuhl M, Arce L, Waldherr R, Conradt C, et al.
Gut
. 2001 Aug;
49(3):418-22.
PMID: 11511565
Background: Epidemiological data indicate an increased risk for rectal cancer following chronic alcohol consumption. As chronic ethanol ingestion leads to rectal hyperregeneration in experimental animals, indicating a state of increased...
5.
Oneta C, Simanowski U, Martinez M, Pares X, Homann N, Conradt C, et al.
Gut
. 1998 Nov;
43(5):612-9.
PMID: 9824340
Background: Ethanol undergoes a first pass metabolism (FPM) in the stomach and liver. Gastric FPM of ethanol primarily depends on the activity of gastric alcohol dehydrogenase (ADH). In addition, the...
6.
Seitz H, Simanowski U, Homann N, Waldherr R
Z Gastroenterol
. 1998 Oct;
36(8):645-55.
PMID: 9773483
Colorectal cell turn over is affected by numerous factors including diets, alcohol consumption, smoking or age and is also significantly changed in certain mucosal diseases including benign and malignant tumors....
7.
Seitz H, Poschl G, Simanowski U
Recent Dev Alcohol
. 1998 Sep;
14:67-95.
PMID: 9751943
A great number of epidemiological data have identified chronic alcohol consumption as a significant risk factor for upper alimentary tract cancer, including cancer of the oropharynx, larynx, and the esophagus,...
8.
Simanowski U, Egerer G, Oneta C, Keil T, Pares X, Conradt C, et al.
Digestion
. 1998 Aug;
59(4):314-20.
PMID: 9693201
Background/aims: Ethanol is metabolized by alcohol dehydrogenase in the human stomach. This metabolism contributes to the so-called first-pass metabolism of ethanol which is affected by gender, medication, and morphological alterations...
9.
Seitz H, Egerer G, Oneta C, Kramer S, Sieg A, Klee F, et al.
Digestion
. 1996 Jan;
57(2):105-8.
PMID: 8785998
Alcohol dehydrogenase (ADH) activities were measured in rectal biopsies from 55 patients (28 males, 27 females aged 22-81 years), in colonic biopsies from 19 patients (10 males, 9 females aged...
10.
Seitz G, Stickel F, Fiehn W, Werle E, Simanowski U, Seitz H
Dtsch Med Wochenschr
. 1995 Mar;
120(12):391-5.
PMID: 7705200
To test the value of carbohydrate-deficient transferrin (CDT) as a marker for chronic alcohol consumption, its concentration was measured in the serum of 74 patients (48 men, 26 women; mean...