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Tyler C Cullender

Explore the profile of Tyler C Cullender including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 2350
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Recent Articles
1.
Cullender T, Chassaing B, Janzon A, Kumar K, Muller C, Werner J, et al.
Cell Host Microbe . 2013 Nov; 14(5):571-81. PMID: 24237702
Gut mucosal barrier breakdown and inflammation have been associated with high levels of flagellin, the principal bacterial flagellar protein. Although several gut commensals can produce flagella, flagellin levels are low...
2.
Carvalho F, Koren O, Goodrich J, Johansson M, Nalbantoglu I, Aitken J, et al.
Cell Host Microbe . 2012 Aug; 12(2):139-52. PMID: 22863420
Colitis results from breakdown of homeostasis between intestinal microbiota and the mucosal immune system, with both environmental and genetic influencing factors. Flagellin receptor TLR5-deficient mice (T5KO) display elevated intestinal proinflammatory...
3.
Koren O, Goodrich J, Cullender T, Spor A, Laitinen K, Backhed H, et al.
Cell . 2012 Aug; 150(3):470-80. PMID: 22863002
Many of the immune and metabolic changes occurring during normal pregnancy also describe metabolic syndrome. Gut microbiota can cause symptoms of metabolic syndrome in nonpregnant hosts. Here, to explore their...
4.
Vijay-Kumar M, Aitken J, Carvalho F, Cullender T, Mwangi S, Srinivasan S, et al.
Science . 2010 Mar; 328(5975):228-31. PMID: 20203013
Metabolic syndrome is a group of obesity-related metabolic abnormalities that increase an individual's risk of developing type 2 diabetes and cardiovascular disease. Here, we show that mice genetically deficient in...