Turgut E Aktepe
Overview
Explore the profile of Turgut E Aktepe including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
316
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Recent Articles
1.
Aktepe T, Deerain J, Hyde J, Fritzlar S, Mead E, Montoya J, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012480.
PMID: 39226332
Norovirus infection is characterised by a rapid onset of disease and the development of debilitating symptoms including projectile vomiting and diffuse diarrhoea. Vaccines and antivirals are sorely lacking and developments...
2.
Deerain J, Aktepe T, Trenerry A, Ebert G, Hyde J, Charry K, et al.
Virology
. 2023 Nov;
589:109921.
PMID: 37939648
Human norovirus is the leading cause of acute gastroenteritis worldwide, however despite the significance of this pathogen, we have a limited understanding of how noroviruses cause disease, and modulate the...
3.
Carrera J, Aktepe T, Earnest L, Christiansen D, Wheatley A, Tan H, et al.
Vaccine
. 2023 Jun;
41(33):4888-4898.
PMID: 37391311
Countermeasures against Zika virus (ZIKV) epidemics are urgently needed. In this study we generated a ZIKV virus-like particle (VLP) based vaccine candidate and assessed the immunogenicity of these particles in...
4.
Heydarchi B, Fong D, Gao H, Salazar-Quiroz N, Edwards J, Gonelli C, et al.
Cell Rep Med
. 2022 May;
3(5):100635.
PMID: 35584627
Human immunodeficiency virus type 1 (HIV-1) vaccination of cows has elicited broadly neutralizing antibodies (bNAbs). In this study, monoclonal antibodies (mAbs) are isolated from a clade A (KNH1144 and BG505)...
5.
Shemesh M, Aktepe T, Deerain J, McAuley J, Audsley M, David C, et al.
PLoS Pathog
. 2021 Dec;
17(12):e1010146.
PMID: 34890433
[This corrects the article DOI: 10.1371/journal.ppat.1009800.].
6.
Shemesh M, Aktepe T, Deerain J, McAuley J, Audsley M, David C, et al.
PLoS Pathog
. 2021 Aug;
17(8):e1009800.
PMID: 34437657
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I...
7.
McAuley J, Deerain J, Hammersla W, Aktepe T, Purcell D, Mackenzie J
mSphere
. 2021 Jun;
:e0031321.
PMID: 34133201
The COVID-19 pandemic has impacted and enforced significant restrictions within our societies, including the attendance of public and professional athletes in gyms. Liquid chalk is a commonly used accessory in...
8.
Mikulasova A, Gillespie L, Ambrose R, Aktepe T, Trenerry A, Liebscher S, et al.
Front Cell Dev Biol
. 2021 May;
9:655606.
PMID: 34055786
Flavivirus replication is intimately associated with re-organized cellular membranes. These virus-induced changes in membrane architecture form three distinct membranous "organelles" that have specific functions during the flavivirus life cycle. One...
9.
Fritzlar S, Aktepe T, Chao Y, Kenney N, McAllaster M, Wilen C, et al.
mBio
. 2019 Jun;
10(3).
PMID: 31213553
The integrated stress response (ISR) is a cellular response system activated upon different types of stresses, including viral infection, to restore cellular homeostasis. However, many viruses manipulate this response for...
10.
Koutsakos M, McWilliam H, Aktepe T, Fritzlar S, Illing P, Mifsud N, et al.
Front Immunol
. 2019 Jun;
10:1158.
PMID: 31191533
Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface expression, is used by many viruses to evade immune recognition. In particular, downregulation of MHC-I molecules at the...