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Tue W Kragstrup

Explore the profile of Tue W Kragstrup including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 317
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Recent Articles
1.
Ferapontov A, Mellemkjaer A, McGettrick H, Vorup-Jensen T, Kragstrup T, Juul-Madsen K
J Transl Autoimmun . 2025 Jan; 10:100266. PMID: 39867459
The family of heterodimeric CD11/CD18 integrins facilitate leukocyte adhesion and migration in a wide range of normal physiologic responses, as well as in the pathology of inflammatory diseases. Soluble CD18...
2.
Gillesberg F, Pehrsson M, Bay-Jensen A, Frederiksen P, Karsdal M, Deleuran B, et al.
Sci Rep . 2025 Jan; 15(1):1087. PMID: 39774197
Understanding how inflammatory cytokines influence profibrogenic wound healing responses in fibroblasts is important for understanding the pathogenesis of fibrosis. TNF-α and IL-13 are key cytokines in Th1 and Th2 immune...
3.
Skaarup L, Ingrid E, Sepriano A, Nikiphorou E, Ostgard R, Lauper K, et al.
Drug Saf . 2024 Jul; 47(11):1075-1093. PMID: 39012469
Background/aim: The purpose of this review is to provide an overview of the contraindications, special warnings, and boxed warnings with the aim to establish a framework to create a prescription...
4.
Yang V, Kragstrup T, McMaster C, Reid P, Singh N, Haysen S, et al.
Drug Saf . 2023 Jul; 46(11):1049-1071. PMID: 37490213
Janus kinase inhibitors (JAKi) have enormous appeal as immune-modulating therapies across many chronic inflammatory diseases, but recently this promise has been overshadowed by questions regarding associated cardiovascular and cancer risk...
5.
Nielsen M, Koster D, Mehta A, Stengaard-Pedersen K, Busson P, Junker P, et al.
Cells . 2023 Jan; 12(2). PMID: 36672263
: Fibroblast-like synoviocytes (FLSs) are essential mediators in the expansive growth and invasiveness of rheumatoid synovitis, and patients with a fibroblastic-rich pauci-immune pathotype respond poorly to currently approved antirheumatic drugs....
6.
Kragstrup T, Sorensen A, Bruner M, Lomholt S, Nielsen M, Schafer P, et al.
Int Immunopharmacol . 2022 Sep; 112:109267. PMID: 36179420
Background: The development of novel treatment strategies of immune-mediated inflammatory arthritis (IMIA) is still a clinical unmet need. The mitogen-activated protein kinase (MAPK) pathway is activated by environmental stressors, growth...
7.
Mikkelsen R, Hundahl M, Torp C, Rodriguez-Carrio J, Kjolby M, Bruun J, et al.
Eur J Pharmacol . 2022 May; 925:174998. PMID: 35533739
Objective: To assess which immunosuppressive drugs have been investigated and proven efficacious in patients with cardiovascular disease (CVD) or type 2 diabetes (T2D) without preexisting immune mediated disorders to validate...
8.
Greisen S, Kragstrup T, Thomsen J, Horslev-Pedersen K, Hetland M, Stengaard-Pedersen K, et al.
Front Immunol . 2022 Mar; 13:773946. PMID: 35356000
Objective: The programmed death-1 (PD-1) pathway is essential for maintaining self-tolerance and plays an important role in autoimmunity, including rheumatoid arthritis (RA). Here, we investigated how membrane-bound and soluble (s)PD-1...
9.
Hansen A, Rahbek L, Sorensen A, Hundahl M, Lomholt S, Holm C, et al.
BMC Immunol . 2021 Dec; 22(1):77. PMID: 34920714
Background: Inflammatory arthritis including rheumatoid arthritis (RA) and spondyloarthritis (SpA) is characterized by inflammation and destruction of the joints. Approximately one third of patients do not respond to first-line treatments....
10.
Kragstrup T, Singh H, Grundberg I, Nielsen A, Rivellese F, Mehta A, et al.
PLoS One . 2021 Jun; 16(6):e0252799. PMID: 34086837
Aims: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to angiotensin converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the infection termed coronavirus disease of...