Tsering Yangzom
Overview
Explore the profile of Tsering Yangzom including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
12
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Recent Articles
1.
Yangzom T, Chen A, Liang K
J Vis Exp
. 2025 Mar;
(216).
PMID: 40029817
The development of midbrain organoids (MOs) from human pluripotent stem cells (hPSCs) represents a significant advancement in understanding brain development, facilitating precise disease modeling, and advancing therapeutic research. This protocol...
2.
Liang K, Chen A, Kianian A, Kristiansen C, Yangzom T, Furriol J, et al.
Int J Biol Sci
. 2024 Jun;
20(8):2860-2880.
PMID: 38904024
Mitochondrial diseases are associated with neuronal death and mtDNA depletion. Astrocytes respond to injury or stimuli and damage to the central nervous system. Neurodegeneration can cause astrocytes to activate and...
3.
Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids
Chen A, Yangzom T, Hong Y, Lundberg B, Sullivan G, Tzoulis C, et al.
Adv Sci (Weinh)
. 2024 Mar;
11(18):e2307136.
PMID: 38445970
In this research, a 3D brain organoid model is developed to study POLG-related encephalopathy, a mitochondrial disease stemming from POLG mutations. Induced pluripotent stem cells (iPSCs) derived from patients with...
4.
Hong Y, Zhang Z, Yangzom T, Chen A, Lundberg B, Fang E, et al.
Int J Biol Sci
. 2024 Feb;
20(4):1194-1217.
PMID: 38385069
Alpers' syndrome is an early-onset neurodegenerative disorder usually caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG), which is essential for mitochondrial DNA (mtDNA)...
5.
Sharma A, Singh S, Bhat M, Gill K, Zaid M, Kumar S, et al.
Sci Rep
. 2023 Sep;
13(1):16420.
PMID: 37775650
Cardiac rhythm regulated by micro-macroscopic structures of heart. Pacemaker abnormalities or disruptions in electrical conduction, lead to arrhythmic disorders may be benign, typical, threatening, ultimately fatal, occurs in clinical practice,...
6.
Marjan S, Yangzom T, Kristiansen C, Chen A, Bindoff L, Liang K
J Vis Exp
. 2023 Aug;
(198).
PMID: 37590511
Mitochondrial dysfunction is a common primary or secondary contributor to many types of neurodegeneration, and changes in mitochondrial mass, mitochondrial respiratory chain (MRC) complexes, and mitochondrial DNA (mtDNA) copy number...
7.
Yangzom T, Tsering D, Kar S, Kapil J
J Lab Physicians
. 2020 Aug;
12(1):3-9.
PMID: 32792787
Bloodstream infections (BSIs) are one of the frequent nosocomial infections among hospitalized patients. To understand the local epidemiology and evolving antimicrobial drug resistance of blood-borne pathogens, we analyzed the distribution...
8.
Yangzom T, Kumar Singh T
J Lab Physicians
. 2019 Oct;
11(3):192-199.
PMID: 31579233
Background: Enterococcus is an important pathogen, and with its emergence of resistance to multiple antimicrobials, the management of infection is becoming increasingly difficult. Aim: The aim of the study is...