Tristin A Schwartze
Overview
Explore the profile of Tristin A Schwartze including associated specialties, affiliations and a list of published articles.
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4
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1
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Recent Articles
1.
Yang W, Hicks D, Ghosh A, Schwartze T, Conventry B, Goreshnik I, et al.
Nat Commun
. 2025 Feb;
16(1):2001.
PMID: 40011465
Immune receptors have emerged as critical therapeutic targets for cancer immunotherapy. Designed protein binders can have high affinity, modularity, and stability and hence could be attractive components of protein therapeutics...
2.
White S, Schwartze T, Mukundan A, Schoenherr C, Singh S, van Dinther M, et al.
Nat Commun
. 2025 Feb;
16(1):1847.
PMID: 39984487
TGM6 is a natural antagonist of mammalian TGF-β signaling produced by the murine helminth parasite Heligmosomoides polygyrus. It differs from the previously described agonist, TGM1 (TGF-β Mimic-1), in that it...
3.
Schwartze T, Morosky S, Rosato T, Henrickson A, Lin G, Hinck C, et al.
J Mol Biol
. 2025 Jan;
437(4):168935.
PMID: 39793884
BMP-9 and BMP-10 are TGF-β family signaling ligands naturally secreted into blood. They act on endothelial cells and are required for proper development and maintenance of the vasculature. In hereditary...
4.
Schwartze T, Morosky S, Rosato T, Henrickson A, Lin G, Hinck C, et al.
bioRxiv
. 2024 Oct;
PMID: 39464140
BMP-9 and BMP-10 are TGF-β family signaling ligands naturally secreted into blood. They act on endothelial cells and are required for proper development and maintenance of the vasculature. In hereditary...
5.
Yang W, Hicks D, Ghosh A, Schwartze T, Conventry B, Goreshnik I, et al.
bioRxiv
. 2024 May;
PMID: 38746206
While there has been progress in the de novo design of small globular miniproteins (50-65 residues) to bind to primarily concave regions of a target protein surface, computational design of...
6.
Cheng Y, Anzell A, Morosky S, Schwartze T, Hinck C, Hinck A, et al.
Cells
. 2024 Feb;
13(3.
PMID: 38334677
Endothelial cells (ECs) respond to concurrent stimulation by biochemical factors and wall shear stress (SS) exerted by blood flow. Disruptions in flow-induced responses can result in remodeling issues and cardiovascular...
7.
White S, Schwartze T, Mukundan A, Schoenherr C, Singh S, van Dinther M, et al.
bioRxiv
. 2024 Jan;
PMID: 38187573
The murine helminth parasite expresses a family of proteins structurally related to TGF-β Mimic 1 (TGM1), a secreted five domain protein that activates the TGF-β pathway and converts naïve T...