Travis Hughes
Overview
Explore the profile of Travis Hughes including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
27
Citations
1291
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0
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Recent Articles
11.
Saruhan-Direskeneli G, Hughes T, Yilmaz V, Durmus H, Adler A, Alahgholi-Hajibehzad M, et al.
Clin Immunol
. 2016 May;
166-167:81-8.
PMID: 27181991
This study aims to investigate genetic susceptibility to early-onset and late-onset anti-acetylcholine receptor antibody positive myasthenia gravis (EOMG and LOMG) and anti-muscle specific kinase antibody positive MG (MuSK-MG) at genome-wide...
12.
Hughes T, Ture-Ozdemir F, Alibaz-Oner F, Coit P, Direskeneli H, Sawalha A
Arthritis Rheumatol
. 2014 Feb;
66(6):1648-58.
PMID: 24574333
Objective: The pathogenesis of Behçet's disease (BD), an inflammatory disease with multisystem involvement, remains poorly understood. This study was undertaken to investigate whether there are DNA methylation abnormalities in BD...
13.
Altorok N, Coit P, Hughes T, Koelsch K, Stone D, Rasmussen A, et al.
Arthritis Rheumatol
. 2014 Feb;
66(3):731-9.
PMID: 24574234
Objective: Primary Sjögren's syndrome (SS) is a systemic autoimmune disease with incompletely understood etiology. This study was undertaken to investigate the role of epigenetic dysregulation in the pathogenesis of primary...
14.
Saruhan-Direskeneli G, Hughes T, Aksu K, Keser G, Coit P, Aydin S, et al.
Am J Hum Genet
. 2013 Jul;
93(2):298-305.
PMID: 23830517
Takayasu arteritis is a rare inflammatory disease of large arteries. The etiology of Takayasu arteritis remains poorly understood, but genetic contribution to the disease pathogenesis is supported by the genetic...
15.
Burris T, Solt L, Wang Y, Crumbley C, Banerjee S, Griffett K, et al.
Pharmacol Rev
. 2013 Mar;
65(2):710-78.
PMID: 23457206
Nuclear receptors are ligand-activated transcription factors and include the receptors for steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as targets for development of myriad drugs that...
16.
Hughes T, Coit P, Adler A, Yilmaz V, Aksu K, Duzgun N, et al.
Nat Genet
. 2013 Feb;
45(3):319-24.
PMID: 23396137
Behçet's disease is an inflammatory disease characterized by recurrent oral and genital ulcers and significant organ involvement. Localizing the genetic association between HLA-B*51 and Behçet's disease and exploring additional susceptibility...
17.
Kaufman K, Zhao J, Kelly J, Hughes T, Adler A, Sanchez E, et al.
Ann Rheum Dis
. 2012 Aug;
72(3):437-44.
PMID: 22904263
Objectives: The Xq28 region containing IRAK1 and MECP2 has been identified as a risk locus for systemic lupus erythematosus (SLE) in previous genetic association studies. However, due to the strong...
18.
Solt L, Wang Y, Banerjee S, Hughes T, Kojetin D, Lundasen T, et al.
Nature
. 2012 Mar;
485(7396):62-8.
PMID: 22460951
Synchronizing rhythms of behaviour and metabolic processes is important for cardiovascular health and preventing metabolic diseases. The nuclear receptors REV-ERB-α and REV-ERB-β have an integral role in regulating the expression...
19.
Sawalha A, Wang L, Nadig A, Somers E, McCune W, Hughes T, et al.
J Autoimmun
. 2012 Feb;
38(2-3):J216-22.
PMID: 22305513
Lupus is less common in men than women, and the reason is incompletely understood. Current evidence indicates that lupus flares when genetically predisposed individuals encounter environmental agents that trigger the...
20.
Hughes T, Adler A, Merrill J, Kelly J, Kaufman K, Williams A, et al.
Ann Rheum Dis
. 2011 Nov;
71(5):694-9.
PMID: 22110124
Objectives: Systemic lupus erythematosus (SLE) is a sexually dimorphic autoimmune disease which is more common in women, but affected men often experience a more severe disease. The genetic basis of...