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Travis Brady

Explore the profile of Travis Brady including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 6
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Recent Articles
1.
Wang D, Brady T, Santhanam L, Gerecht S
Nat Cardiovasc Res . 2024 Aug; 2(8):718-732. PMID: 39195965
Mechanical stimuli from the extracellular matrix (ECM) modulate vascular differentiation, morphogenesis and dysfunction of the vasculature. With innovation in measurements, we can better characterize vascular microenvironment mechanics in health and...
2.
Wang H, Martinez Yus M, Brady T, Choi R, Nandakumar K, Smith L, et al.
Am J Physiol Heart Circ Physiol . 2024 Jul; 327(3):H642-H659. PMID: 39028284
Hypertension, a disease with known sexual dimorphism, accelerates aging-associated arterial stiffening, partly because of the activation of matrix remodeling caused by increased biomechanical load. In this study, we tested the...
3.
Steppan J, Wang H, Nandakumar K, Gadkari M, Poe A, Pak L, et al.
Am J Physiol Lung Cell Mol Physiol . 2024 Jul; 327(4):L423-L438. PMID: 39010824
Conduit pulmonary arterial stiffening and the resultant increase in pulmonary vascular impedance have emerged as an important underlying driver of pulmonary arterial hypertension (PAH). Given that matrix deposition is central...
4.
Santhanam L, Wang H, Martinez Yus M, Brady T, Choi R, Nandakumar K, et al.
bioRxiv . 2024 Jan; PMID: 38168163
Background: Hypertension, a disease with known sexual dimorphism, accelerates aging associated arterial stiffening, in part due to the activation of matrix remodeling caused by increased biomechanical load. In this study,...
5.
Steppan J, Wang H, Nandakumar K, Poe A, Pak L, Brady T, et al.
bioRxiv . 2023 Nov; PMID: 37961202
Background: Conduit pulmonary arterial stiffening and the resultant increase in pulmonary vascular impedance has emerged as an important underlying driver of pulmonary arterial hypertension (PAH). Given that matrix deposition is...
6.
Steppan J, Nandakumar K, Wang H, Jang R, Smith L, Kang S, et al.
Physiol Rep . 2023 Apr; 11(7):e15656. PMID: 37038896
Hypoxia in the neonatal period is associated with early manifestations of adverse cardiovascular health in adulthood including higher risk of hypertension and atherosclerosis. We hypothesize that this occurs due to...
7.
Elliott M, Matsushita H, Shen J, Yi J, Inoue T, Brady T, et al.
Acta Biomater . 2022 Aug; 151:134-147. PMID: 35933100
Thrombogenicity poses a challenge to the clinical translation of engineered grafts. Previously, small-diameter vascular grafts (sdVG) composed of fibrin hydrogel microfiber tubes (FMT) with an external poly(ε-caprolactone) (PCL) sheath supported...