Toshio Narahashi
Overview
Explore the profile of Toshio Narahashi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
583
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Moriguchi S, Tagashira H, Sasaki Y, Yeh J, Sakagami H, Narahashi T, et al.
J Neurochem
. 2013 Oct;
128(6):927-37.
PMID: 24164423
Because the cholinergic system is down-regulated in the brain of Alzheimer's disease patients, cognitive deficits in Alzheimer's disease patients are significantly improved by rivastigmine treatment. To address the mechanism underlying...
2.
Moriguchi S, Tanaka T, Narahashi T, Fukunaga K
Hippocampus
. 2013 Jun;
23(10):942-51.
PMID: 23733502
Sunifiram is a novel pyrrolidone nootropic drug structurally related to piracetam, which was developed for neurodegenerative disorder like Alzheimer's disease. Sunifiram is known to enhance cognitive function in some behavioral...
3.
Moriguchi S, Tanaka T, Tagashira H, Narahashi T, Fukunaga K
Behav Brain Res
. 2013 Jan;
242:150-7.
PMID: 23295391
Alzheimer's disease (AD) shows degeneration of the cholinergic system in the medial septum, thereby eliciting down-regulation of the olfactory function in patients. We have previously reported that olfactory bulbectomized (OBX)...
4.
Narahashi T
Curr Protoc Toxicol
. 2012 Oct;
Chapter 11:Unit11.10.
PMID: 23045088
This overview gives brief accounts of the mechanism of nerve excitation, receptor/channel functions, cable properties of neurons, and voltage clamp and patch clamp principles. Among various aspects of electrophysiology, emphasis...
5.
Hasaka M, Mori T, Matsuura T, Narahashi T, Kuno M, Asada A, et al.
Neuroreport
. 2012 Jun;
23(10):601-5.
PMID: 22664778
The purinergic P2X4 receptors (P2X4Rs) of spinal microglia are upregulated after a peripheral nerve injury and play important roles in the pathogenesis of chronic pain. The effects of general anesthetics...
6.
Matsuura T, Mori T, Hasaka M, Kuno M, Kawawaki J, Nishikawa K, et al.
J Physiol
. 2011 Dec;
590(4):827-44.
PMID: 22183729
Voltage-gated proton channels play crucial roles during the respiratory burst in phagocytes, such as microglia. As local anaesthetics have a variety of anti-inflammatory properties, including inhibition of phagocytosis, they may...
7.
Song J, Marszalec W, Kai L, Yeh J, Narahashi T
Brain Res
. 2011 Dec;
1435:15-23.
PMID: 22177663
Proton channels are gated by voltage and pH gradients, and play an important role in the microglial production of pro-inflammatory cytokines, which are known to be suppressed by antidepressants. In...
8.
Glutamate-activated chloride channels: Unique fipronil targets present in insects but not in mammals
Narahashi T, Zhao X, Ikeda T, Salgado V, Yeh J
Pestic Biochem Physiol
. 2010 Jun;
97(2):149-152.
PMID: 20563240
Selectivity to insects over mammals is one of the important characteristics for a chemical to become a useful insecticide. Fipronil was found to block cockroach GABA receptors more potently than...
9.
Moriguchi S, Han F, Shioda N, Yamamoto Y, Nakajima T, Nakagawasai O, et al.
J Neurochem
. 2009 May;
110(1):170-81.
PMID: 19457128
Aberrant behaviors related to learning and memory in olfactory bulbectomized (OBX) mice have been documented in the previous studies. We reported that the impairment of long-term potentiation (LTP) of hippocampal...
10.
Moriguchi S, Shioda N, Han F, Yeh J, Narahashi T, Fukunaga K
Hippocampus
. 2009 Mar;
19(9):844-54.
PMID: 19253410
Galantamine, a novel Alzheimer's drug, is known to inhibit acetylcholinesterase activity and potentiate nicotinic acetylcholine receptor (nAChR) in the brain. We previously reported that galantamine potentiates the NMDA-induced currents in...