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Toshihiro Nakano

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Articles 9
Citations 62
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Recent Articles
1.
Nakano T, Shiizaki K, Miura Y, Matsui M, Kosaki K, Mori S, et al.
Sci Rep . 2019 Dec; 9(1):19247. PMID: 31848393
Circulating levels of fibroblast growth factor-21 (FGF21) start increasing in patients with chronic kidney disease (CKD) since early stages during the cause of disease progression. FGF21 is a liver-derived hormone...
2.
Karasawa K, Uchida K, Nakano T, Moriyama T, Nitta K
Clin Nephrol . 2018 Jul; 90(3):222-226. PMID: 30049299
As immunotactoid glomerulopathy (ITG) is a very rare primary glomerular disease, no standard treatment has been established. It has been reported that ITG progresses to end-stage renal disease at a...
3.
Sawada A, Kawanishi K, Morikawa S, Nakano T, Kodama M, Mitobe M, et al.
BMC Nephrol . 2018 Mar; 19(1):72. PMID: 29587650
Background: Vancomycin is the first-line antibiotic for methicillin-resistant Staphylococcus aureus and coagulase-negative strains. The risk of vancomycin-induced acute kidney injury increases with plasma vancomycin levels. Vancomycin-induced acute kidney injury is...
4.
Nakano T, Ohki I, Yokota A, Ashida H
PLoS One . 2013 Jul; 8(7):e67385. PMID: 23840871
To recycle reduced sulfur to methionine in the methionine salvage pathway (MSP), 5-methylthioribulose-1-phosphate is converted to 2-keto-4-methylthiobutyrate, the methionine precursor, by four steps; dehydratase, enolase, phosphatase, and dioxygenase reactions (catalyzed...
5.
Nakano T, Saito Y, Yokota A, Ashida H
Biosci Biotechnol Biochem . 2013 May; 77(5):1104-7. PMID: 23649237
The methionine salvage pathway (MSP) recycles reduced sulfur from 5-methylthioribose. Here we propose a novel ribose metabolic pathway performed by MSP enzymes of Bacilli. MtnK, an initial catalyst of MSP,...
6.
Nakano T, Saito Y, Yokota A, Ashida H
Biochem Biophys Res Commun . 2013 Jan; 431(2):176-80. PMID: 23313478
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and RuBisCO-like protein (RLP) from Bacillus subtilis catalyze mechanistically similar enolase reactions. Both enzymes require carbamylation of the ε-amino group of the active site lysine during activation...
7.
Koga F, Tanaka H, Takamatsu S, Baba S, Takihara H, Hasegawa A, et al.
World J Clin Oncol . 2012 May; 3(4):63-6. PMID: 22574289
A 70-year-old man was referred to our hospital due to abnormal liver function. A tumor of 92 mm × 61 mm was detected on ultrasound screening of the left liver...
8.
Nakano T, Ashida H, Mizohata E, Matsumura H, Yokota A
Biochem Biophys Res Commun . 2010 Jan; 392(2):212-6. PMID: 20060808
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and RuBisCO-like protein (RLP) catalyze similar enolase-type reactions. Both enzymes have a conserved non-catalytic Lys122 or Arg122 on the beta-strand E lying in the interface between the...
9.
Ashida H, Saito Y, Nakano T, de Marsac N, Sekowska A, Danchin A, et al.
J Exp Bot . 2008 Apr; 59(7):1543-54. PMID: 18403380
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the key enzyme in the fixation of CO(2) in the Calvin cycle of plants. Many genome projects have revealed that bacteria, including Bacillus subtilis, possess genes...