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Torben Elm

Explore the profile of Torben Elm including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 166
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Recent Articles
1.
Carol Illa A, Hvid H, Elm T, Frederiksen C, Bangshof L, Danielsen D, et al.
Biol Open . 2025 Feb; 14(2). PMID: 39912492
Well-characterised mouse models of disease may provide valuable insights into pathophysiology. This study characterises the Townes mouse model of sickle cell disease (SCD) and establishes a time window in which...
2.
Gandhi P, Zivkovic M, Ostergaard H, Bonde A, Elm T, Lovgreen M, et al.
Nat Cardiovasc Res . 2024 Aug; 3(2):166-185. PMID: 39196196
Inherited bleeding disorders such as Glanzmann thrombasthenia (GT) lack prophylactic treatment options. As a result, serious bleeding episodes are treated acutely with blood product transfusions or frequent, repeated intravenous administration...
3.
Stagaard R, Ovlisen G, Klaebel J, Danielsen D, Lund A, Elm T, et al.
J Thromb Haemost . 2023 Jan; 21(5):1189-1199. PMID: 36696187
Background: Preclinical bleeding models increase current hemophilia A (HA) knowledge and aid the development of new pharmacological treatments. There are several well-established mouse bleeding models, but limited options are available...
4.
Carol Illa A, Baumgarten S, Danielsen D, Larsen K, Elm T, Johansen P, et al.
J Vis Exp . 2021 Oct; (175). PMID: 34661578
Tail bleeding models are important tools in hemophilia research, specifically for the assessment of procoagulant effects. The tail vein transection (TVT) survival model has been preferred in many settings due...
5.
Stennicke H, Kjalke M, Karpf D, Balling K, Johansen P, Elm T, et al.
Blood . 2013 Jan; 121(11):2108-16. PMID: 23335368
Frequent infusions of intravenous factor VIII (FVIII) are required to prevent bleeding associated with hemophilia A. To reduce the treatment burden, recombinant FVIII with a longer half-life was developed without...
6.
Ostergaard H, Bjelke J, Hansen L, Petersen L, Pedersen A, Elm T, et al.
Blood . 2011 Jun; 118(8):2333-41. PMID: 21700771
Current management of hemophilia B entails multiple weekly infusions of factor IX (FIX) to prevent bleeding episodes. In an attempt to make a longer acting recombinant FIX (rFIX), we have...
7.
Petersen L, Elm T, Ezban M, Krogh T, Karpf D, Steino A, et al.
Thromb Haemost . 2009 May; 101(5):818-26. PMID: 19404533
The mechanism for the elimination of factor VII (FVII) from the circulation is unknown, just as it is unclear how activation of FVII to FVIIa and subsequent complex formation with...
8.
Andersson E, Axelsson J, Pedersen L, Elm T, Andersson R
Scand J Gastroenterol . 2007 May; 42(6):765-70. PMID: 17506000
Objective: Acute pancreatitis starts as an autodigestive process restricted to the pancreas and progresses to a systemic inflammation via cytokine release into the blood stream. Several inhibitors of the coagulation...
9.
Gram D, Hansen A, Wilken M, Elm T, Svendsen O, Carr R, et al.
Eur J Endocrinol . 2005 Dec; 153(6):963-9. PMID: 16322403
Objective: It has earlier been demonstrated that capsaicin-induced desensitization improves insulin sensitivity in normal rats. However, whether increased capsaicin-sensitive nerve activity precedes the onset of insulin resistance in diet-induced obesity--and...
10.
Petersen L, Norby P, Branner S, Sorensen B, Elm T, Stennicke H, et al.
Thromb Res . 2005 Apr; 116(1):75-85. PMID: 15850611
Tissue factor (TF) is believed to play an important role in coagulation, inflammation, angiogenesis and wound healing as well as in tumor growth and metastasis. To facilitate in vivo studies...